One hundred years of insulin. Type 2 diabetes mellitus is a chronic, progressive disease that frequently necessitates treatment with basal insulin to maintain adequate glycaemic control... O Svik - Norwegian Medical Association 被引量: 0发表: 2020年 The effect of intensive treatment of diabetes on...
54 EFFECT OF ONE YEAR TREATMENT WITH INSULIN AND ORAL GLUCOSE-LOWERING AGENTS ON LIPID LEVELS IN NON-OBESE PATIENTS WITH TYPE 2-DIABETESdoi:10.1016/s1567-5688(11)70055-1S. Sgaard LundL. TarnowB. NielsenB. HansenM. FrandsenO. Pedersen...
A major effect of insulin is its ability to stimulate the synthesis of glycogen in skeletal muscle. By 'working backwards' from glycogen synthesis, we have dissected an insulin-stimulated protein kinase cascade which is triggered by the activation of PtdIns 3-kinase. The first enzyme in this ...
In the present study, we further investigated the effect of gestrinone on the development of uterine leio- myoma, and the expression of c-Src, phospho-416Src, ER, and PR in the guinea pig model. Materials and methods Materials Gestrinone microparticle (13β-ethyl-17α- ethynyl-17β-...
(LOAD) patients [100]. Additionally, it was found that platelet expression of TLR-4 was upregulated in AD subjects compared to control [73,101]. Further research into platelet TLR-4 and TLR-2 could prove promising, especially when considering the effect of Aβ) on inducing platelet TLR ...
Effect of PA on inflammation and oxidative stress in middle cerebral artery occlusion (MCAO) rats. Effects of PA on the levels of IL-6 (A), IL-1β (B), SOD (C), and GSH-Px (D) in brain homogenates from rats. The ratio of female to male rats was 1:1. Data were presented as...
[6] C Barnett, DL Costill, MD Vukovich, KJ Cole, BH Goodpaster, SW Trappe, WJ Fink.Effect of L-carnitine supplementation on muscle and blood carnitine content and lactate accumulation during high-intensity sprint cycling. Int J Sport Nutr. 1994 Sep; 4(3): 280-8. ...
[12] M Yoshioka, S St-Pierre, V Drapeau, I Dionne, E Doucet, M Suzuki, A Tremblay.Effects of red pepper on appetite and energy intake. Br J Nutr. 1999 Aug; 82(2): 115-23. [13] MP Lejeune, EM Kovacs, MS We...
Meanwhile, insulin-like growth factor 1 (IGF-1) and intercellular adhesion molecule 1 (ICAM-1) protein levels were increased in a dose-dependent manner. Our findings illustrated that formononetin exhibits a protective effect on HUVECs, and the molecular mechanisms may correlate with IGF-1R and...
In fact, the aggregation of insulin in the presence of the proteins was higher than that of insulin alone, suggesting that α-Clu and β-Clu co-precipitated out with insulin. Yeast ADH aggregates at a temperature of 48 °C. Figure 2b shows the effect of α-Clu and β-Clu on the ...