the Large Bowel, Great BritainFlat Lesions Most lesions not truly flat8Soetikno, JAMA 2008Normal to Adenoma to CarcinomaNormal Polyp Cancer9Human colon carcinogenesis 鈼 mismatch repair (microsatellite instability) pathwaySymptoms of Colorectal Cancer Early colon cancer usually presents with no symptoms...
This chronic inflammation can lead to the accumulation of genetic mutations, DNA damage, and ultimately the transformation of normal gastric epithelial cells into cancerous cells. Additionally, H. pylori produces virulence factors such as the cytotoxin-associated gene A (CagA) and vacuolating cytotoxin...