A total of 104 patients with low simple intersphincter anal fistulas who meet the inclusion criteria will be included in this trial and will be allocated randomly to two groups (test and control groups). The patients in the test group will receive one-stage anal fistulotomy surgery combined ...
40]. Initial platelet adhesion to the blood vessel wall under high-shear stress is achieved by the binding of the (GP)Ib-IX-V complex on platelet cell surface to von Willebrand factor (vWF) expressed on endothelial cells and
2a: The technique of anal fistulotomy with shaped skin harvesting and grafting at the surgical wound in one stage for healing the low simple intersphincter anal fistula: study protocol for a multicentre random controlled trial 2b: Chinese Clinical Trial Register, ID: ChiCTR2000039174. Registered ...
The metabolome represents a complex network of biological events that reflects the physiologic state of the organism in health and disease. Additionally, specific metabolites and metabolic signaling pathways have been shown to modulate animal ageing, but
Integrative analysis of large-scale single-cell RNA sequencing (scRNA-seq) datasets can aggregate complementary biological information from different datasets. However, most existing methods fail to efficiently integrate multiple large-scale scRNA-seq da
Intermittent fasting (IF), consisting of either a one-day (IF1) or two consecutive days (IF2) per week, is commonly used for optimal body weight loss. Our laboratory has previously shown an IF1 diet combined with 6d/week of protein pacing (P; 4–5 meals/day evenly spaced, ~ 30...
Also, this type of chronic pain has no purposes of adaptation, devoid of biological value, not respond to typical treatment and last more than six months, causing suffering, distress and contributing to deteriorate the quality of life of the patients44. Several screening tools have been developed...
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The incidence of rabies in Thailand reached its peak in 2018 with 18 human deaths. Preexposure prophylaxis (PrEP) vaccination is thus recommended for high-
This allowed for further examination and analysis of the cellular changes and morphology within the brain tissues. Cell experiments The PC12 cells used in this study were provided by the Chinese Academy of Medical Sciences. To cultivate the PC12 cells, a glass flask containing DMEM enriched with...