INSULIN therapyDIABETESBackground: In purpose‐bred dogs, insulin glargine 300 U/mL (IGla300) has long duration of action, peakless time‐action profile, and low potency, making it suitable for use as a basal insulin. Hypothesis: To evaluate IGla300 in client‐owned diabetic dogs...
Slow-acting basal insulin, typically injected daily, can help stabilize glucose levels between meals in individuals with diabetes. But results from a
Credit: Pixabay/CC0 Public Domain In the Phase 3a ONWARDS 5 randomized trial, once-weekly insulin icodec titrated with a dosing guide app demonstrated superior reduction in HbA1c levels and similarly low hypoglycemia rates compared with once-daily insulin. The findings are published inAnnals of Int...
We compare the efficacy and safety of once-daily biphasic insulin aspart 70/30 (BIAsp 30) and insulin glargine in Asian subjects with type 2 diabetes inadequately controlled with oral anti-diabetic drugs (OADs). In a 26-week, open-labelled, randomised, parallel-group, multinational, multicentre...
Figure 1. Flow of Participants in a Trial of Once-Weekly Insulin Icodec vs Once-Daily Insulin Degludec for Type 2 DiabetesView LargeDownload There were no study- or country-level important protocol deviations during the trial. There were 26 important site-level protocol deviations, 68 at the ...
(EQW) with titrated insulin detemir in patients with type 2 diabetes inadequately controlled with metformin (with or without sulfonylureas).RESEARCH DESIGN AND METHODS-Patients were randomized to EQW (2 mg) or detemir (once or twice daily, titrated to achieve fasting plasma glucose = 1.0kg at ...
Efficacy of once-daily insulinThe article presents a study which aims to determine the efficacy of simple once-a-day insulin regimen for type 2 diabetes in England.Critical Care Alert
Effects of once-daily biphasic insulin aspart 30 with metformin versus twice-daily biphasic insulin aspart 30 in South African type 2 diabetes subjectsP. NaikerH.A. MakanT. KedijangL.L.L. KongM.A.K. Omar
Effects of twice-daily Vs. once-daily slow release tacrolimus on the insulin resistance indexes in kidney transplant patientsV., CademartoriF., MassarinoE.L., ParodiR., RussoA., SofiaI., FontanaG.L., VivianiG., Garibotto
Twenty patients were changed from a single daily injection of beef insulin (a mixture of soluble and protamine zinc insulin) to two daily injections (mixtures of soluble and isophane insulins). This was associated with a reduction, one month later, in the concentration of glycosylated haemoglobin...