ON-switch的一个蛋白质结构域与每条CAR链融合,导致在添加药物后分裂的CAR完全组装,从而在抗原结合时激活CAR T细胞。在AbCID-CAR和hRBP4 ON-switch-CAR中,ON-switch的一个结构域在CAR链内表达,而第二个结构域是另外包含抗原结合 scFv 的可溶性链的一部分。添加药物会导致可溶性链和膜结合链相互作用,从而在遇到抗原...
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PROBLEM TO BE SOLVED: To provide an on-car safety switch of an elevator which can be surely operated from a car stop side at a start of next maintenance work.OKAZAKI TOSHIKI岡崎 俊樹NAKAMURA HIROYUKI中村 裕之HARADA SATOSHI原田 聡OTSUKA TOSHIKI大塚 俊輝YAZAWA YOSHIKI矢澤 良樹...
She felt his weight pinning her to the back seat of the car. She felt his arm tight against her throat, squeezing. Felt her wrists in handcuffs behind her back. Duct tape stretched around her head, covering her nose and mouth.【USA...
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