The aim of this study was to determine the effect of time intervals between BCS and RT on 10-year DFS, LRRFS, DMFS and OS in Dutch breast cancer patients. To achieve this, we investigated two populations: one in which patients receiving chemotherapy before RT were excluded, in order to ...
Introduction Non-pharmacotherapy based interventions (NPTs) and Viscum album extracts (VA) are integral part of integrative oncology (IO) and support conventional cancer therapies to meet patients' needs and reduce chemotherapy induced side effects. NPTs are introduced in IO to activate patients' reso...
in free form, and the chemotherapy drug was loaded in NDDS [97]. Li et al. have reported TME-activatable prodrug vesicle for co-loading oxaliplatin (OXA) prodrug and photosensitizer (PS), which would produce immunogenic cell death (ICD) of the tumor cells [98]. The prodrug vesicle was co...
DAMPs. DAMPs have immunostimulatory properties when exposed to or secreted by dying cells. DAMPs are excreted during necrosis under inflammatory or pathological conditions. Several lines of evidence show that cancer cells exposed to chemotherapy or radiotherapy can produce DAMPs, recruit, and activate imm...
of birth. We also extracted all entries with ICD10 code ‘Z511’, which codes for an ‘encounter for antineoplastic chemotherapy and immunotherapy’. Two fathers of individuals with hypermutation who we suspect had chemotherapy before conception did not meet these criteria as the father of GEL_5...
Nanomaterials can target cancer tissues to deliver ICD inducers and co-load versatile immunostimulants to enhance the immunogenicity of in situ cancer vaccines. In addition to traditional chemotherapy drugs that induce ICD in cancer cells, such as DOX, oxaliplatin, and mitoxantrone, other types of ...
It is well established that the anticancer immune response determines the success of anthracycline-based adjuvant chemotherapy of breast cancer. This effect is in part due to the capacity of anthracyclines to induce immunogenic cell death (ICD), a cell death modality that is preceded by autophagy ...
- 《Japanese Journal of Chemotherapy》 被引量: 10发表: 1999年 Evaluation of CT and MRI Findings among Patients Presented with Chief Complaint of Headache in Central India sinusitis in 58 (11.6%), bone related pathology in 26 (5.2%) and chronic suppurative otitis media (CSOM) in 13 (2.6%...
Relevance of timing on treatment response to CDK4/6i-based combination therapy. First-line therapy with platinum-based chemotherapy (CTX) triggers resistance and impedes response to CDKi (upper part). Addition of EGFR-blocking antibody cetuximab can partially suspend resistance. However, in case of...
(ICD)-inducing chemotherapy and immunotherapy, CRMs potentially enhance the efficacy of cancer treatments through synergistic effects.234Preclinical studies have shown that STF, which serves as an adjunct to various cancer treatments, may bolster antitumor immunity by attenuating immunosuppressive conditions ...