Integration of metagenomic and metataxonomic sequencing data with other omics data to study the gut microbiome has become increasingly common, but downstream analysis after data integration and interpretation of complex omics data remain challenging. Here, we review studies that have explored the gut ...
The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles during periods of human health and disease. Cell Host Microbe 16, 276–289 (2014). Article CAS Google Scholar Zhou, Y. & Zhi, F. Lower level of Bacteroides in the gut microbiota is associated with ...
dorei proteome (https://www.uniprot.org/proteomes/UP000005974), a microbial genome database (https://biocore.github.io/wol/) and a human gut microbiome database (https://db.cngb.org/microbiome/genecatalog/genecatalog_human/). Source data are available for in vitro and in vivo experiments....
In the gut microbiome, the gut microbiota transmit signals to the brain through pathways associated with neural transmission and control of behaviors [22]. Depression has been associated with gut dysbiosis, an imbalance of the gut microbiota that is associated with adverse health outcomes [23,24]....
Understanding the emergence and spread of antibiotic resistance genes (ARGs) in wildlife is critical for the health of humans and animals from a “One Health” perspective. The gut microbiota serve as a reservoir for ARGs; however, it remains poorly understood how environmental and host genetic fa...
Establishment and analysis of grass carp gut microbiome gene catalogues.ATaxonomic annotation of the grass carp gut gene catalog at the super kingdom level. Only non-redundant genes that could be classified from the NCBI nr database were involved in the analysis.BandCThe NR genes assigned to ba...
Gut Microbiome and Metabolomics: Unraveling the Metabolic Impact on Human Health Metabolic Flux Analysis: A Comprehensive Overview Real-Time Metabolomics: Advancing Dynamic Monitoring of Metabolic Changes Challenges in Metabolomics Bioinformatics Top 10 questions asked in metabolomics ...
gut microbiome in inducing or alleviating the development of disease following variants of Koch’s postulates [9,10,11]. Given that the composition of the human microbiota is highly dynamic and can be altered with drugs or dietary interventions [12], the microbiome has been proposed as a ...
The human microbiome contains ~7,000 species and ~1,000,000 genes, and most of it is located in the gut (1). The microbiota is heterogeneous and dynamic: it changes with age, diet, and health status (2). Numerous aspects of host physiology are influenced by the gut microbiota, ...
Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease. United Eur. Gastroenterol. J. 6, 1496–1507 (2018). Article CAS Google Scholar Ramirez-Perez, O., Cruz-Ramon, V., Chinchilla-Lopez, P. & ...