Overview About the Olfactory transduction pathway Within the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be transmitted to the brain. Odorant molecules bind to ...
Intracellular cascade of enzymes induced by the binding of odorants to odorant receptors. The interaction between an odorant and its cognate receptor induces a transduction pathway, involving the...Marc D. BinderNobutaka HirokawaUwe WindhorstSpringer Berlin HeidelbergEncyclopedia of Neuroscience...
Olfactory transduction refers to the process by which odor molecules bind to receptors in the cilia of olfactory receptor cells, leading to the activation of a cascade of biochemical reactions that ultimately result in the electrical response to odor stimulation. ...
ShepherdGordon M.Nature Publishing Group UKNatureShepherd. G. M.: Olfactory Transduction: Welcome Whiff of Biochemistry. Nature 316 (1985), S.214f.Shepherd GM (1985) Olfactory transduction: Welcome whiff of biochemistry. Nature 316:214–215....
Olfactory transductionbegins when an odour molecule binds to aG proteincoupledolfactory receptor(OR) on the surface of asensory neuron[2]. InDrosophila,theseolfactory receptor neurons(ORNs) are concentrated in two peripheral appendages, the third antennal segments and the maxillary palps (Fig. 1A)....
【7.2.7】嗅觉信号转导(Olfactory Signal Transduction) 嗅觉是最原始的感觉功能之一,起着识别、报警、增强食欲、影响情绪等作用,因此,嗅觉产生的分子机制长期以来一直是神经分子生物学研究的焦点之一。但是,关于人如何识别和记忆约一万种不同气味的原理却知之甚少。2004年诺贝尔生理学或医学奖得主Richard Axel和Linda ...
Although olfaction has captured the attention of scientists and philosophers alike for most of recorded history, it is only during the past twenty years that our present understanding of odor detection (transduction) has begun to emerge. In 1972, Kurihar
摘要: An unusual chloride current seems to play an important role in safeguarding olfactory transduction against an unstable ionic environment, and in nonlinearly amplifying the olfactory signal.DOI: 10.1016/S0960-9822(00)00058-0 被引量: 102 ...
During the past 150 years, researchers have investigated the cellular, physiological, and molecular mechanisms underlying the sense of smell. Based on these efforts, a conclusive model of olfactory signal transduction in the vertebrate's nose is now available, spanning from G-protein-mediated odorant...
Stimulus transduction in cilia of olfactory sensory neurons is mediated by odorant receptors, Gαolf, adenylate cyclase-3, cyclic nucleotide-gated and chloride ion channels. Mechanisms regulating trafficking and localization of these proteins in the dend