Olfactory dysfunction is a common symptom of OCD, but all previous studies have focused on late-onset OCD (LOCD). Methods: The current study compared olfactory identification ability in EOCD patients and age-matched and sex-matched LOCD patients and healthy controls. Thirty patients with EOCD, ...
A retrospective study of 750 patients tested at the University of Pennsylvania concluded that "chemosensory dysfunction influences quality of life."4 In particular, patients with dysosmia or dysgeusia had higher scores on the Beck Depression Inventory, indicating more severe depression, than patients wit...
it is not always the case. Patients commonly develop hallucinations on doses of drugs that have not been changed in several years. The association of diminished vision with visual hallucinations brings to mind Bonnet's syndrome, in which elderly people with severe visual dysfunction but normal...
Here, we assessed olfactory function at both levels in patients with schizophrenia through a series of unirhinally administered tests. In our experiments, we did not observe any difference in olfactory processing when testing both of a subject's nostrils, which suggests that dysfunc...
Diminished inhibitory control is frequently associated with maladaptive eating behaviour58,59, which could also relate more directly to olfactory dysfunction. Thus, the assessment of olfactory function has broad importance in the clinical setting. Olfactory functioning was not predictive of the ability to...
However, little is known about how age-related olfactory dysfunction develops over time and how such decline is related to decline in other non-olfactory cognitive domains. Most evidence regarding effects of age on olfactory functions is based on cross-sectional observations, but such data is ...
Childhood trauma heightened vulnerability to olfactory dysfunction (B=0.721, 95% CI [0.671, 0.724]), subsequently exacerbating internalizing problems (B=0.311, 95% CI [0.226, 0.408]). This effect persisted in longitudinal data (abuse:B=0.686,p<0.001; neglect:B=0.200,p<0.001). Regarding ...
The olfactory bulb (OB) receives extensive cholinergic input from the basal forebrain and is affected very early in Alzheimer’s disease (AD). We speculated that an olfactory ‘stress test’ (OST), targeting the OB, might be used to unmask incipient AD. We investigated if change in olfactory...
Henkin RI, Martin BM, Agarwal RP (1999) Decreased parotid saliva gustin/carbonic anhydrase VI secretion: an enzyme disorder manifested by gustatory and olfactory dysfunction. Am J Med Sci 318(6):380–391Henkin RI, Martin BM, Agarwal RP (1999) Decreased parotid saliva gustin/carbonic anhydrase...
Schizophrenia shows high heritability and several of the genes associated with this disorder are involved in calcium (Ca2+) signalling and synaptic function. One of these is the Rab-3 interacting molecule-1 (RIM1), which has recently been associated with