Olfaction declines with aging and appears to be a prodromal sign of cognitive decline in progressive neurodegenerative diseases. Nevertheless, very little is known about the pathophysiological changes underlying smell loss that may reflect early network dysfunction. A cross-sectional histoanatomical study ...
Doty RL, Shaman P, Applebaum SL, Giberson R, Siksorski L, Rosenberg L (1984) Smell identification ability: changes with age. Science 226(4681):1441–1443 Article CAS Google Scholar Dyck M, Loughead J, Kellermann T, Boers F, Gur RC, Mathiak K (2011) Cognitive versus automatic mechanis...
Olfactory function plays a key role in human life [1] regulating food ingestion, emotional responses, social and reproductive behavior [2]. Olfactory function decreases over the lifespan [3,4,5] and approximately 5% of the general population exhibits functional anosmia [6]. People with olfactory ...
Dietary intake, dietary patterns, and changes with age: an epidemiological perspective. J Gerontol A Biol Sci Med Sci.2001;56:65-80.Google Scholar 58. Schiffman SS, Warwick AS. Effect of flavor enhancement of foods for the elderly on nutritional status: food intake, biochemical indices and ...
plays a major role in the persistent long-term changes associated with learning, memory, and cognitive functions. The intricate balance between LTP and LTD processes plays a major role in the encoding and storage of new, incoming information [7]. The natural processes of aging damage and destroy...
Doty RLShaman PApplebaum SLGiberson RSiksorski LRosenberg L Smell identification ability changes with age. Science.1984;226:1441-1443.PubMedGoogle Scholar 15. Hall JR Patterns of Fire Casualties in Home Fires by Age and Sex, 1990-1994. Quincy, Mass: National Fire Protection Association; 1997...
Changes in the taste system with age may be related to nutrient intake, which in turn can be influenced by taste. Literature on such interrelationships is limited. Vitamins A, thiamin, B-6, B-12, folacin, zinc, and copper are thought to influence taste function. Moreover, those nutrients ...
Olfactory training (OT) has been shown to increase olfactory performance in healthy subjects and patients with post-traumatic or post-infectious olfactory loss. Morphological correlates such as olfactory bulb volume increase and gray matter changes suggest central changes in olfactory brain areas following...
Olfactory Dysfunction Associated with Aging As with other sensory modalities, the sense of smell decreases with age. For instance, while about one-fifth of the general population has diminished olfaction,[32]about two-thirds of individuals aged 80 and older have olfactory decline.[33]Age-associated...
The location of neuropathological changes in AD patients indicates the potential diagnostic utility of olfactory tests. The purpose of this study was to compare odor identification performance among Polish subjects and to define the correlation between olfactory deficits and cognitive impairment. Olfactory...