Olanzapine for intractable nausea and vomiting in palliative care patients not receiving chemotherapy 机译:奥氮平用于未接受化疗的姑息治疗患者的顽固性恶心和呕吐 获取原文 获取原文并翻译 | 示例 掌桥外文数据库(机构版) >> 开具论文收录证明 >> 文献代查 >> 页面...
Although it has been administered at a number of facilities, its applicability to treat nausea and vomiting in patients with advanced cancer is poorly understood. We investigated the use of olanzapine for nausea and vomiting in patients with advanced cancer at multiple centers. This retrospective ...
"It's well-appreciated by most people that patients receivingcancerchemotherapy suffer fromnauseaand vomiting," explains Dr. Loprinzi. "However, it's less well-appreciated that patients withadvanced canceralso have significant problems with nausea and vomiting that are unrelated to chemotherapy." Drs....
Current research has identified several receptors that trigger nausea and vomiting, hence the difficulty of using only 1 medication to provide relief. Olanzapine is a drug approved for treatment of schizophrenia and mania. It blocks multiple neurotransmitters dopaminergic, serotonergic, adrenergic (alpha(...
Olanzapine, a generic drug used to treat nervous, emotional and mental conditions, also may help patients with advanced cancer successfully manage nausea and vomiting unrelated to chemotherapy. These are the findings of a study published Thursday, May 7 inJAMA Oncology. ...
Olanzapine as an add‐on, pre‐operative anti‐emetic drug for postoperative nausea or vomiting: a randomised controlled trial Olanzapine is an antipsychotic drug that is used to prevent nausea and vomiting in palliative care and to treat chemotherapy‐induced nausea and vomiting. ... TR Grigio,H...
Olanzapine is also effective in reducing breakthrough nausea and vomiting. In a randomized study, patients with breakthrough vomiting or moderate to severe nausea were treated with olanzapine; 70% had no further vomiting and 68% had no further nausea (compared with 31% and 23%, respectively, wi...
Olanzapine has shown effectiveness in relieving chemotherapy-induced nausea and vomiting, particularly when combined with 5-HT3 receptor antagonists (5-HT3RAs), such as ondansetron or palonosetron, which block serotonin receptors to reduce nausea, ...
Vig S, Seibert L, Green MR (2014) Olanzapine is effective for re- fractory chemotherapy-induced nausea and vomiting irrespective of chemotherapy emetogenicity. J Cancer Res Clin Oncol 140:77-82Vig S, Seibert L, Green MR (2014). Olanzapine is effective for refractory chemotherapy-induced ...
Number needed to be treated (NNT) improved on increasing dose of olanzapine from 5mg to 10mg for prevention of both nausea (48%) and vomiting (36%) in comparison to placebo. In the 0–2h postoperative time interval, complete response (CR) rates were insignificant (P=0.48, P=0.11) for ...