The concentration-to-dose ratio of olanzapine was found to vary by 26-fold in 56 patients with schizophrenia given olanzapine 5 to 20 mg/day as monotherapy and as comedication.[51] A minimum effective therapeutic plasma concentration of 9 μg/L was established from a study of 79 inpatients ...
Olanzapine is a commonly prescribed atypical antipsychotic medication that frequently causes weight gain. To our knowledge, the neural correlates of this weight gain have not been adequately studied in humans. Objective To test the hypothesis that olanzapine treatment disrupts the neural activity ...
As there are novel biological treatment options for further investigation in AN, such as psilocybin and ketamine, as well as non-invasive brain stimulation treatments on the horizon, olanzapine may not be the preferred medication for people with AN and their clinicians. However, these treatments are...
Although we found a significant difference in the effi- cacy of the medication among groups, the sample size of this study was small. Clinical trials with a larger sample size are required to confirm the results of this study in the future. Conclusion In this study, we found that in ...
During clinic visits in April and May, she was euthymic and without complaints. Then, in June, concerned that her weight had increased from 110 to 118 pounds, she abruptly discontinued her medication... 展开 关键词: Humans Fluoxetine Benzodiazepines Drug Combinations Risk Factors Patient Compliance...
is an atypical antipsychotic medication with once-daily dosing that was originally developed for the treatment of sch... Z Daniel,Lieberman,K Frederick,... - 《Expert Review of Neurotherapeutics》 被引量: 12发表: 2004年 Affective Disorders 2: Bipolar Disorder Summary Bipolar disorder is ...
placebo-controlled study of youth aged 10–17 where OFC was significantly superior to placebo in reducing symptoms of depression in this population (Detke et al., 2015). Until recently, OFC was the only medication with FDA-approval for the treatment of bipolar depression in youth (s...
(risperidone three of three (100%), olanzapine one of two (50%), haloperidol one of two (50%), F=0.857, df=2, p=0.49), or treated with any concomitant mood medication initially (risperidone five of six (83%), olanzapine five of six (83%), haloperidol four of 10 (40%), F=...
, who was blinded to the drug being administered, recorded the following information every 24 hours for the first 120 hours after the initiation of HEC or MEC: use of any rescue medication for CINV, the number and time of any emetic events, and maximum nausea experienced, which was rated ...
Thus, the relative benefits of two medications can only be fully understood by comparing the changes achieved when switching from one medication to the other and vice versa. To better understand the clinical implications of switching between risperidone and olanzapine in the ‘real world’ setting, ...