AjitWestShahWestEBSCO_AspInternational Journal of Geriatric PsychiatryShah A. Can risperidone and olanzapine in elderly patients with dementia and other mental disorders be discontinued? Int J Geriatr Psychiatry 2006; 21: 140-6.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of olanzapine in the elderly. However, elderly patients are more likely to have dementia or age-related liver, kidney, or heart problems, which may require caution or an adjustment...
摘要: Study Objectives. To compare the effects of risperidone and olanzapine on cognition in elderly patients with dementia and psychosis, and to compare the side effects of these drugs.Design. Single-blind, multicenter, observational study.
Olanzapine may cause serious side effects such as an increased risk of death or stroke in elderly patients with dementia, a higher risk of suicide when taken with fluoxetine, metabolic changes, tardive dyskinesia, low blood pressure, and blood cell disorders. See the warnings below for a full ...
However, dosage modification should be considered for patients characterised by a combination of factors associated with decreased oxidative metabolism, for example, debilitated or elderly women who are nonsmokers.This is a preview of subscription content, log in via an institution to check access. ...
Elderly patients withdementia fluoxetinein combination, also refer to the boxed warning section of the package insert for Symbyax. Common side effects Common side effects seen with olanzapine are: an inability to sit still (akathisia), constipation, ...
Elderly patients are particularly vulnerable to adverse drug reactions as a result of polypharmacy and metabolic changes associated with aging. We present a case of leukocytoclastic vasculitis induced by olanzapine, a medication commonly used in elderly patients. An 82-year-old woman was admitted to...
The recommended starting dosage of olanzapine is 5 to 10mg(1 to 5mg in elderly patients) once daily, regardless of meals. If clinically indicated, 5mg increments or decrements at intervals of at least 1 week may be implemented, up to a maximum recommended dosage of 15 mg/day. The effective...
Objective: Although a growing body of research suggests that atypical neuroleptic medications are efficacious in the treatment of cocaine addiction among i... Smelson,DA,Ziedonis,... - 《J Clin Psychopharmacol》 被引量: 72发表: 2006年 Olanzapine in the treatment of elderly patients with schizophr...
Olanzapine/fluoxetine dosage adjustments are recommended in patients with hepatic impairment and in those who have a combination of factors that may affect olanzapine or fluoxetine metabolism; caution is advised in elderly patients. Several pharmacokinetic drug interactions have been shown to occur between...