• Lorazepam (IM):Increased somnolence with IM olanzapine. ( 7.2) • Other Concomitant Drug Therapy:When using olanzapine in combination with lithium or valproate, refer to the Drug Interactions sections of the package insert for those products. ( 7.2) Use In Specific Populations • Preg...
Olanzapine IM is a short-acting formulation that may be given to adults with schizophrenia or bipolar I mania if they have become agitated. The usual dosage of olanzapine IM is 10 mg as a single dose. Smaller dosages (5 mg or 7.5 mg) can be given if these are more appropriate. ...
Oral ZYPREXA and fluoxetine in combination is indicated for the treatment of depressive episodes associated with bipolar I disorder, based on clinicalstudies. When using ZYPREXA and fluoxetine in combination, refer to the Clinical Studies section of the package insert for Symbyax. ZYPREXA monotherapy is...
Olanzapine may antagonize the effects of levodopa and dopamine agonists. Lorazepam (IM) Co-administration of lorazepam does not significantly affect the pharmacokinetics of olanzapine, un conjugated lorazepam, or total lorazepam. However, this co-administration of lorazepam with olanzapine potentiated the s...
agitation Hideaki Katagiri1*, Shinji Fujikoshi1, Takuya Suzuki2, Kiyoshi Fujita3, Naoya Sugiyama4, Michihiro Takahashi1,6 and Juan-Carlos Gomez5 Abstract Background: Olanzapine rapid-acting intramuscular (IM) injection is an atypical antipsychotic drug already used overseas and recently approved in ...
(olanzapine incidence at least twice that for placebo)during the placebo-controlled premarketing studies. The incidence of somnolence during the 24 hour IM treatment period in clinical trials in agitatedpatients with schizophrenia or bipolar I mania was 6% for intramuscular olanzapine for injection and...
(olanzapine incidence at least twice that for placebo)during the placebo-controlled premarketing studies. The incidence of somnolence during the 24 hour IM treatment period in clinical trials in agitatedpatients with schizophrenia or bipolar I mania was 6% for intramuscular olanzapine for injection and...