Compared with valproate semisodium 500 to 2500 mg/day (in divided doses) olanzapine 5 to 20 mg/day improved symptoms of mania (according to Y-MRS total score) to a significantly greater extent (49vs37%, p < 0.05) in a 3-week double-blind trial of patients (n = 251) with either m...
Olanzapine 5 to 20 mg/day was significantly superior to haloperidol 5 to 20 mg/day in overall efficacy in apost hocanalysis of a cohort with first-episode psychosis from a large double-blind trial, but was of similar efficacy to haloperidol 2 to 20 mg/day in preliminary results of a pros...