PURPOSE:To obtain a new compound for treating and alleviating inflammatory diseases, allergy and cardiovascular diseases, having lipoxygenase inhibiting activity. CONSTITUTION:A compound shown by formula I (A is 1-6C alkylene or 2-6C alkenylene; Yn is H, halogen, OH, CN, 1-12C haloalkyl, etc...
DANKAN ROBAATOSON REISAMYUERU JOOJI GIBUSON
Displacement N ((4 piperidinyl) alkyl) two cyclic condensation okisazo - ru - and chiazo - ru - aminesNovel substituted N- (4-piperidinyl)alkyl! bicyclic condensed oxazol- and thiazolamines useful as anti-depressives, in the treatment of Parkinson's disease and in the treatment of diseases...
CONSTITUTION:A compound expressed by formula I (R<1> is organic residue with influence under cyclization condition; R<2> is lower alkyl) is subjected to cyclization reaction in the presence of preferably acetic anhydride to afford an oxazole derivative expressed by formula II (R<3> is formyl ...