This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant ...
John Anson, CEO of OGT commented, "With this expansion of our SureSeq portfolio, we have further broken down the barriers for hybridization in NGS, making it quicker, easier and more flexible, while also delivering enormous benefits to researchers in terms of data quality. OGT has a reputat...
We then applied small interfering RNA to deplete KIF1A mRNA in LNCaP-AI cells and overexpressed KIF1A expression in LNCaP and DU145 cells. KIF1A knockdown decreased expression of NE marker (NCAM1, ENO2, and SYP) in LNCaP-AI cells, while KIF1A overexpression increased those protein expression ...
ASXL1 plays key roles in epigenetic regulation of gene expression through methylation of histone H3K27, and disruption of ASXL1 drives myeloid malignancies, at least in part, via derepression of posterior HOXA loci. However, little is known about the identity of proteins that interact with ASXL1...