分别在0.5、1、3、6、9、12、24和48 hours post-infection (hpi)收集样品,通过RT-qPCR检测ASFV-CP204L和ASFV-B646L基因的转录水平,结果显示,O8、S-克唑替尼和TH588对早期基因CP204L的转录具有显著抑制效果,对晚期基因B646L的...
2011.7.29痒痒舜舜击掌视频从04:00开始https://app.cctv.com/special/m/livevod/index.html?vtype=2&guid=b4127b236521498491487dc2a142aa83 来自Android客户端101楼2024-12-18 11:44 回复 三点半睡觉专家 冠军捧花 11 1111111111111 点击展开,查看完整图片 来自Android客户端102楼2024-12-18 11:53 回复 三...
(NUP98)重组蛋白 Ⅰ类主要组织相容性复合体C(MHCC)重组蛋白 Ⅰ类主要组织相容性复合体E(MHCE)重组蛋白 Ⅹ型胶原(COL10)重组蛋白 ⅩⅢ型胶原(COL13)重组蛋白 ⅩⅧ型胶原(COL18)重组蛋白 88KDA核孔蛋白(NUP88)重组蛋白 ⅡA组磷脂酶A2(PLA2G2A)重组蛋白 ⅣD组磷脂酶A2(PLA2G4D)重组蛋白 ⅩⅤ型胶原(COL...
NM002542-9 pCMV-Tag 2A 全长 N-Flag 哺乳细胞 2800 NM002542-10 pCMV-Tag 4A 全长 C-Flag 哺乳细胞 2800 NM002542-11 pCMV-HA 全长 N-HA 哺乳细胞 2800 NM002542-12 pEGFP-C1 全长 N-EGFP 哺乳细胞 2800 NM002542-13 pEGFP-N1 全长 C-EGFP 哺乳细胞 2800 NM002542-14 p3xFlag-CMV-10 全长 ...
-Ogg1 protein level was significantly reduced (80%) in 0 cells as determined by western blot analysis (Figure 2A and C). These contradictory results suggested that either ?-Ogg1 is regulated differentially in 0 or is not the major 8-oxoG DNA glycosylase in human mitochondria. Thus, we ...
inhibitory factor 1 (WIF1), TIMP metallopeptidase inhibitor 2 (TIMP2), TIMP metallopeptidase inhibitor 3 (TIMP3), mutL homolog 1 (MLH1), cyclin-dependent kinase inhibitor 2A (CDKN2A), secreted frizzled related protein 4 (SFRP4), and secreted frizzled related protein 5 (SFRP5)) [86], which...
2a). In parallel, knockout of endonuclease III-like protein I (Nth1), the BER enzyme specially repairing thymine glycol, reduced H2O2-induced parthanatos to ~50% (Fig. S4), suggesting that OGG1 expression is more decisive in oxidative stress-induced cell death. To further affirm the effect...
Overexpression of OGG1-2a in SNU423 cells, which have low mtOGG1 levels, effectively recovered cellular respiration and cell growth activities, and decreased intracellular ROS. Taken together, our results suggest that mtOGG1 plays an important role in maintaining mitochondrial respiration, thereby ...
(52 upregulated genes, 63 downregulated genes,Hdac1cKO versus controls; Supplementary Fig.2a). To understand how HDAC1 regulates these genes, we performed HDAC1 chromatin immunoprecipitation (ChIP) followed by sequencing (ChIP-seq) using hippocampal tissues from young wild-type animals. We identified ...
By RT-PCR analysis, five novel type 1 transcripts, in addition to eight known types (OGG1-types 1a to 1c and 2a to 2e), were identified. Among them, only the type 1a isoform contains both a nuclear localization signal and the entire DNA binding motif, suggesting the involvement of type...