In an open clinical trial study, thirty-six pneumonia are treated by ofloxacin 200 mg t.i.d. All pneumonia are confirmed by chest X Ray and bacteriological data was always obtained, sputum cultures were not taken into account. 41 bacteria were isolated included 12 S. pneumoniae and 10 H. ...
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Objective To study the pharmacokinetics of balofloxacin in healthy volunteers after oral administration. Methods Three different doses(100,200,400 mg) of balofloxacin was taken separately to 12 healthy volunteers in tri-cycle crossover for an open randomized three groups. The plasma concentration of...
In an open study a total of 30 hospitalized patients suffering from bronchial infections were given ofloxacin, 200 mg b.i.d. orally for an average duration of 9 days. Prior to therapy sputum was collected for bacteriological examination and relevant pathogens (⩾ 10 6 CFU/ml) were isolated...
Ofloxacin 400 mg once daily or ciprofloxacin 200 mg twice daily were given intravenously for at least 3 days followed by oral treatment with ofloxacin 400 mg once daily or ciprofloxacin 500 mg twice daily. Overall cure rates of 86.8% (85.7%) in the ofloxacin group and 89.6% (89.5%) in ...
Compares the efficacy and safety of 400 mg fleroxacin given once daily and 200 mg ofloxacin given twice daily administered orally for seven to fourteen days for the treatment of complicated urinary tract infection (UTI) among hospitalized urologic patients. Cure rates; Comparable efficacy and safety ...
In phase one; each subject was given 600 mg of rifampicin (usual adult dose) with 350 mL of water each. Two weeks later they received 600 mg rifampicin plus 200 mg ofloxacin with 350 mL of water, which serves for the second phase and finally, 600 mg rifampicin plus 400 mg norfloxacin ...
dosage of 200 mg loading followed by 25 mg/L of peritoneal dialysate achieved overnight trough peritoneal levels which are at least four times the minimal 90% inhibitory concentration (MIC90) of most bacterial pathogens without significant accumulation in the systemic circulation. This i.p. dosage...
OfloxacinSafetyClinical trial4196 patients with miscellaneous infections (2334 outpatients and 1862 inpatients) received ofloxacin during clinical trials in France from 1986 to 1989. Mean age was 57.4 卤 18.4 y.o. (male 2199, female 1997). OFL was administered at the dosage of 200 mg b.i.d....