At the very beginning of Of Mice and Men, Steinbeck uses the following two parallel sentences, each beginning with the word "both," to compare Lennie and George: "Both were dressed in denim trousers and in denim coats with brass buttons. Both wore black, shapeless hats and both carried tig...
a, Meta-regression analysis examining the association between the number of sessions applied and the effect size in adults, either on overall health benefits (left, 469 in part dependent effect sizes from 85 studies and 103 cohorts) or for physical (middle, 245 in part dependent effect sizes f...
Discussion Based on this nationwide survey of the Chinese adult general population, we found that chronic exposure to residential outdoor LAN was positively associated with blood glucose levels, insulin resistance and diabetes prevalence, and inversely associated with beta cell function; these associations...
Learning about ho foreigners are USUaW PerCeVed and treated by the local people. Identifying Difference: HOW We AddreSS EaCh Other Questions SrdiSCUSSion O⅛hase Q 0缙? USUaW We Can address a friend from an ιgl⅛sh*SPeaking CoUntry by hb/her fir$t rame WithOUt ment⅛oning his/her...
Discussion This study demonstrated that AGD1 is highly expressed in exosomes derived from PCSCs. Functional experiments showed that both exogenous and endogenous AGD1 reduced the therapeutic efficacy of docetaxel in CRPC by promoting the stemness of CRPC cells in vitro and in vivo. Mechanistically,...
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Drug delivery technologies have enabled the development of many pharmaceutical products that improve patient health by enhancing the delivery of a therapeutic to its target site, minimizing off-target accumulation and facilitating patient compliance. As
Discussion SPHERE is the first large study aimed to explore EVs as a novel potential mechanism of how air pollution exposure acts in a highly susceptible population. The rigorous study design, the availability of banked biological samples and the potential to integrate epidemiological, clinical and mo...
Using data of the National Nutrition Survey in Switzerland (menuCH), we aimed to describe intakes of dairy and its subcategories, to compare daily and per-meal dairy protein with total protein intake, and to investigate associations between energy-standardized dairy intake and sociodemographic, life...
Durations are defined by a beginning and an end, and a major distinction is drawn between durations that start in the present and end in the future (‘prospective timing’) and durations that start in the past and end either in the past or the present (‘retrospective timing’). Different...