Franjic and colleagues performed sn-RNA-seq on cells from five subregions of the entorhinal-hippocampal complex from six human donors, as well as on samples from rhesus macaques and pigs [57]. They compared their data with published single-cell sequencing data from mice and observed...
A well-functioning placenta is essential for fetal and maternal health throughout pregnancy. Using placental weight as a proxy for placental growth, we report genome-wide association analyses in the fetal (n = 65,405), maternal (n = 61,228) a
Flow chart. Established cell line models (ECLM), primary tumor models (PTM), genetically engineered models (GEM). *One record was initially screened negative on the abstract, and the other two studies were found through other literature (one as a historical perspective and the other as an ECLM...
Using network pharmacology and molecular docking technology, proteomics and experiments were used to verify the effect of Yigu decoction (YGD) on the expression of key genes in osteoporotic mice Kun Yan, Rui-Kun Zhang, Jia-Xin Wang, Hai-Feng Chen, Yang Zhang, Feng Cheng, Yi Jiang, Min Wang...
Molecular characterization of heat shock-like factor encoded on the human Y chromosome, and implications for male infertility. Biol Reprod. 2004;71:297–306. Article CAS PubMed Google Scholar Stahl PJ, Mielnik AN, Barbieri CE, Schlegel PN, Paduch DA. Deletion or underexpression of the Y-...
Hepatocyte nuclear factor 4α (HNF4α) and glucocorticoid receptor (GR), master regulators of liver metabolism, are down-regulated in fatty liver diseases. The present study aimed to elucidate the role of down-regulation of HNF4α and GR in fatty liver and hyperlipidemia. Methods Adult mice wi...
Scientometric characterization of epigenetic inheritance studies The first papers on the epigenetic inheritance of metabolic traits via the paternal lineage date back to 1998 [15,16]. The number of publications per year has been increasing steadily at a 1.9 papers/year rate (r2 = 0.771) althou...
Chartreusin Streptomyces chartreusis Influenza A Miyakawa et al. (1958) Mannose specific pradimicin-A (PRMA) Actinomadura hibisca HIV Tanabe-Tochikura et al. (1990) Actinohivin Longispora albida gen. nov, sp. nov HIV Chiba et al. (2004); Takahashi et al. (2005) Benzastatin C, a ...
Synthesis and Characterization 6-amino-oxoisoaporphine, La; 8-amino-oxoisoaporphine, Lb; 8-chloro-oxoisoaporphine, Lc; and 10-chloro-11-amino-oxoisoaporphine, Ld; were synthesized according to reported procedures44,45,46. Acylation of 4-chloro phenylethylamine or β-phenylethylamine with phthalic...
High-density lipoprotein (HDL) is considered to be an anti-atherogenic lipoprotein moiety. Generation of genetically modified (total body and tissue-specific knockout) mouse models has significantly contributed to our understanding of HDL function. Here