Thus, a precise characterization of the GM is of crucial significance for hosts health and disease. 1.1.1. Taxonomic features of the gut microbiome Although initial knowledge about the human GM was derived from labor-intensive culture-based methods, the introduction of culture-independent sequencing ...
In my third year, I elected to compute stellar-structure models in an elective lab together with another enthusiastic student. To this day, I don’t think we deserved the grade that we were given; neither we nor the teaching assistant who graded us understood the importance of the outer bou...
Dr. Katherine Maloney: I disagree with him. I think he's wrong. … I think she likely died sometime between like 5 a.m. and 1 p.m. Timing of the death seemed crucial. If Cathy was murdered in the dead of night, before Jim Krauseneck went to work, then prosecutors say her killer...
The mevalonate pathway plays a critical role in multiple cellular processes in both animals and plants. In plants, the products of this pathway impact growth and development, as well as the response to environmental stress. A forward genetic screen ofArabidopsis thalianausing Ca2+-imaging identified ...
Another manifestation of phenotypic plasticity is the dedifferentiation process, which plays a crucial role in several tumors including melanoma. As a matter of fact, melanoma cells undergo a phenotypic switch due to loss of melanocytes specific gene expression and increase of mesenchymal markers leading...
It is most important not to misinterpret iNKLPD as extranodal NK/T-cell lymphoma, the immunophenotype of which can be largely identical with the exception of crucial differential EBV association. While the infiltrate of atypical medium-sized lymphoid cells is worrisome, the small size and ...
The transcription factor family activator protein 2 (TFAP2) is vital for regulating both embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding proteins, including TFAP2A, TFAP2B, TFAP2C, TFAP2D and TFAP2E. The importance of T
recipient soil and how introduced microbiomes affect the resident microbial community. Furthermore, considering the increasing use of microbial inoculants and consortia [18,19,20], it is crucial to understand how biotic disturbances influence soil microbial interactions and their potential impact on ...
brauneri are relatively shorter compared to those found in extant mayfly larvae, thus, the role of these filaments in respiration was probably not as crucial. Still, even short filaments increased the surface area of the flap and could aid respiration. Interestingly the abdominal tracheal gills of...
It is of crucial importance to most types of cells that the Ca2+concentration in the ER ([Ca2+]ER) does not drop below a certain level, since the activity of ER chaperones such as calreticulin and calnexin strictly depends on free Ca2+[26]. These lectin chaperones are responsible for prop...