Tamoxifen is associated with an increased incidence of endometrial cancer in women. It is also a potent carcinogen in rat liver and forms covalent DNA adducts in this tissue. A previous study exploring DNA adducts in human endometria, utilizing thin layer chromatography 32 P-postlabelling, found ...
A team of US-based researchers has found an association between indicators of longer estrogen exposure and reduced brain shrinkage in midlife women. The findings are published today in the scientific journal, Neurology.
Consider more natural methods of contraception and hormone replacement –there are plenty of choices now for contraception. If you’ve been on the pill for a long time, consider switching. You can also swap from synthetic HRT toBody Identical HRT, a much safer alternative. Supplements– supplemen...
It should therefore prove valuable for screening, particularly in the management of menopausal women requiring oestrogen treatment... JD Hutton,AR Morse,MC Anderson,... - 《Br Med J》 被引量: 69发表: 1978年 Treatment BACKGROUND: When the mechanism of action behind treatment toxicity reflects th...
Tamoxifen has been the endocrine treatment of choice for all stages of oestrogen receptor positive breast cancer for 20 years and the first chemical therap... DJ Bentrem,P Gaiha,VC Jordan - 《Ejc Supplements》 被引量: 49发表: 2003年 Estrogen and progesterone receptors in gallbladder cancer Br...
women gain weight at the time of menopause, they feel like they’re going a little ‘crazy’ or their life is way out of control. It’s also a time we see increased facial hair, especially of the moustache variety. We’re forgiven for ‘dreading’ those transition years but as we ...
and breast milk. Measurement of urinary phytoestrogen excretion is considered a reliable indication of dietary phytoestrogen intake. Concentrations of metabolites can vary within individuals even in a controlled setting of isoflavone and lignan supplements. This is attributed to the variation in metabolism ...
Impact of adjuvant therapy on quality of life in women with node-positive operable breast cancer. International Breast Cancer Study Group. Adjuvant therapy for early breast cancer is effective but may be toxic. Our aim was to investigate the impact of the presence, timing, and duration of adju...
Tamoxifen has been the endocrine treatment of choice for all stages of oestrogen receptor positive breast cancer for 20 years and the first chemical therapeutic to be tested to reduce the incidence of breast cancer in high-risk women. It is now clear that the oestrogen receptor is proving to ...
For women using HRT and COCs,...doi:10.1016/S1359-6349(06)80264-8J. MarsdenR. A'HernK. BriggsC. DawsonJ. BlissElsevier LtdEjc Supplements