Armstrong BK 1988 Oestrogen therapy after the menopause - boon or bane? Medical Journal of Australia 148 213-214.Armstrong BK: Oestrogen therapy after the menopause — boon or bane? Med J Austral 148:213–214, 1988.Armstrong BK. Oestrogen therapy after menopause — boon or bane? Med J Aust...
The Women's International Study of long Duration Oestrogen after Menopause (WISDOM) developed from a joint initiative of the UK Medical Research Council (MRC) and the UK Departments of Health. At the start of the WISDOM trial observational studies had suggested that long term use of estrogen was...
Several studies have shown that oestrogen treatment after menopause decreases the risk for Alzheimer's disease (AD). It is also known that oestrogen stimulates the outgrowth of nerve cells and that apolipoprotein E (Apo E) synthesis and amyloid precursor protein (APP) metabolism are regulated by ...
用作名词(n.) And women with big hips are thought to have high levels of oestrogen. 一般认为女性屁股大与雌激素过高有关。 Many women with breast cancer are given drugs to stop oestrogen production. 许多患乳腺癌的妇女需服用药物抑制雌激素的产生。
After menopause, and the decline in circulating oestrogen, rodents and humans develop increased fat mass, glucose intolerance and abnormalities in temperature regulation; oestrogen replacement therapy blunts these effects20,21. Oestrogen actions are primarily mediated by oestrogen receptors (ERa, b), ...
4.The menopause is a natural part of ageing and usually occurs between 45 and 55 years of age after levels of the hormone oestrogen have declined to the point where ovulation and menstruation stop. 5.Fertility is indicated because a narrow waist is linked to higher oestrogen levels. ...
After menopause, women are at an increased risk to develop visceral obesity due to the loss of endogenous ovarian hormone production. Effects of oestrogens are classically mediated by the two nuclear oestrogen receptors (ERs) and . In addition, more recent research has shown that the intracellular...
At menopause, the synthesis of ovarian hormones ceases. However, oestrogen continues to be converted from androgen (produced by the adrenal glands) by the cytochrome P-450-dependent enzyme, aromatase [20]. This biological pathway served as the basis for the development of the anti-aromatase class...
Although menopausal status has not been shown to be a significant modifier of the alcohol-breast cancer association (Trentham-Dietz et al, 2014), the majority of breast cancer cases are diagnosed after menopause, with elevated circulating oestro- gens being a strong risk factor (Key et al, ...
N. Leaf HRT for treating menopause: known unknowns Bmj, 381 (2023), p. p1364 CrossrefView in ScopusGoogle Scholar [6] G.A. Petroianu Hyperthermia and serotonin: the quest for a "better cyproheptadine" Int. J. Mol. Sci., 23 (2022) Google Scholar [7] I.P. Voronova 5-HT receptors...