Journal of Clinical PathologyAckroyd R, Brown NJ, Stephenson TJ, Stoddard CJ, Reed MW. Ablation treatment of Barrett’s esophagus: what depth of tissue destruction is needed. J Clin Pathol 1999;52:509–12.Ackroyd R, Brown NJ, Stephenson TJ, et al. Ablation treatment for Barrett oesophagus:...
The FHCC study incorporated multi-regional, longitudinal sampling from before and at cancer diagnosis. We examined the development of ecDNA over time in biopsies from patients with Barrett’s oesophagus tissue that progressed to an EAC end-point versus those patients with Barrett’s oesophagus tissue ...
A tissue-engineered oesophageal scaffold could be very useful for the treatment of pediatric and adult patients with benign or malignant diseases such as carcinomas, trauma or congenital malformations. Here we decellularize rat oesophagi inside a perfusi
Early detection of Barrett's oesophagus is confined to research settings; however, there are promising chemoprevention strategies. Proton pump inhibitors (PPIs) effectively reduce acid reflux, which is thought to be one of the main drivers of Barrett's oesophagus. After the development of Barrett's...
Granular cell tumour is a relatively uncommon, typically benign neoplasm of soft tissue. The macroscopic appearance of oesophageal granular cell tumour is a polypoid lesion, which is often asymptomatic and can be found incidentally, but, in some cases, is symptomatic and requires a correct ...
The oesophagus is a complex tissue that poses several challenges to clinically successful grafting. First, the oesophagus is multi-layered so requires engineering of all structural compartments for its reconstruction. Transplanting of appropriate cells appears to be key to promote fast, complete and func...
Conclusions: Plasma and tissue levels of MIC-1/GDF15 are significantly elevated in patients with BO, LGD and OAC. Plasma MIC-1/GDF15 may have value in diagnosis and monitoring of Barrett's disease. Barrett's oesophagus (BO) is an acquired condition in which the normal squamous lining of ...