Many patients with mild oesophagitis are asymptomatic, but more severe inflammation often causes pain on swallowing (odynophagia), retrosternal burning or dysphagia. The endoscopic appearance varies from a few small white and raised plaques (Fig. 1) to elevated confluent plaques with hyperaemia and...
Precipitating causes of acid reflux episodes in ambulant patients with gastro-oesophageal reflux disease. Previous studies of the mechanisms that precipitate acid reflux episodes have used short term hospital based measurements. A 24 hour pH and motility recording system, incorporating a sphincter monitorin...
The practical management of Eosinophilic oesophagitis presents with challenges, due to, among other causes, the current lack of availability of specific drugs, and its approach with, occasionally complex, diet treatments. The present document, prepared by the Working Group on Eosinophilic Gastrointestinal...
2010).Thecausesunderlyingthisdramaticincreaseare poorlyunderstood,anditisunfortunatelynotpossibleto predictwhichpatientshavethehighestriskofdeveloping EAC.Barrett’soesophagus(BE),definedasapathologi- caltransformationofthenormalsquamousoesophagus epitheliumintometaplastic intestinal-like epithelium, is ...
Oesophagitis arises when reflux of acid from the stomach into the oesophagus causes mucosal inflammation. It is a common problem and a systematic review on the optimum treatment would be useful. To assess the effectiveness of proton pump inhibitors (PPIs), H2 receptor antagonists (H2RAs), pro...
The pathological features resemble nonspecific aortoarteritis. Altered reaction to tuberculous infection and other possible aetiological causes are discussed.doi:10.1007/BF02664042Solomon VictorV JayanthiJayabaulS SridharN MadanagopalanSpringer IndiaIndian Journal of Thoracic & Cardiovascular Surgery...
Eosinophilic oesophagitis(EoE) and gastro-oesophageal reflux disease(GORD) are the most common causes of chronic oesophagitis and dysphagia associated with oesophageal mucosal eosinophilia. Distinguishing between the two is imperative but challenging due to overlapping clinical and histological features. A ...
When this causes breaks in the oesophageal lining, it is termed erosive oesophagitis. In the UK, the management of erosive oesophagitis can be separated into two phases: healing and maintenance. For healing, a gold-standard treatment is lansoprazole, a proton-pump-inhibitor (PPI). Recent ...
It is important to systematically assess multiple possible causes of non-response, as well as consider treatment complications and an incorrect diagnosis of EoE. If non-response is confirmed, second-line treatments are required. Although the overall response rate for second-line therapy is ...
Eosinophilic oesophagitis(EoE) and gastro-oesophageal reflux disease(GORD) are the most common causes of chronic oesophagitis and dysphagia associated with oesophageal mucosal eosinophilia. Distinguishing between the two is imperative but challenging due to overlapping clinical and histological features. A ...