Any commercial use of this material is subject to written permission from the OECD. OECD GUIDELINE FOR TESTING OF CHEMICALS Acute Dermal Irritation/Corrosion INTRODUCTION 1. OECD Guidelines for Testing of Chemi
TestGuideline404(TG404);adoptedin1981andrevisedin1992and2002)(2).Inrelationtoanimal15 welfareTG404wasrevisedin2002,allowingforthedeterminationofskincorrosionbyapplyingatiered16 testingstrategy,usingvalidatedinvitroorexvivotestmethods,thusavoidingpainandsufferingof17 ...
Version 4.0 September 30, 2008 OECD GUIDELINE FOR THE TESTING OF CHEMICALS DRAFT PROPOSAL FOR A REVISED GUIDELINE 413 Subchronic Inhalation Toxicity: 90-Day Study SUMMARY This revised Test Guideline 413 (TG 413) has been designed to fully characterize test article toxicity by the inhalation ...
OECD Guideline for Testing of Chemicals, Mammalian Erythrocyte Micronucleus Test. Document No. 474, adopted July 21.OECD, "OECD guideline for testing of chemicals," OECD #474, 1997.OECD, 1997a. OECD Guideline for Testing of Chemicals, Bacterial Reverse Mutation Test. Document No. 471, ...
OECD GUIDELINE FOR THE TESTING OF CHEMICALS DRAFT PROPOSAL FOR A NEW GUIDELINE Fish Embryo Toxicity (FET) Test INTRODUCTION 1. This Test Guideline describes a Fish Embryo Toxicity (FET) test mainly developed for use with the zebrafish (Danio rerio) but the test method can also be ad...
1. This test guideline has been designed to provide information on absorption of a test substance applied to excised skin. It can either be combined with the OECD Test Guideline for Skin Absorption: ByÁ t Method (1), or be conducted separately. It is recommended that the OECD ...
1.OECDGuidelinesfortheTestingofChemicalsareperiodicallyreviewedinthelightofscientific progressorchangingassessmentpractices.TheoriginalGuideline420wasadoptedinJuly1992asthe firstalternativetotheconventionalacutetoxicitytest,describedinTestGuideline401.Basedonthe
This system includes for OECD three levels of testing (ready and inherent biodegradability tests, simulation tests). It was adopted by many countries and is completely integrated into European legislation (registration, evaluation, authorization, and restriction of chemicals, REACH). Nevertheless, the ...
TheOECD, based in Paris, France, has had an extensive environmental program since the 1970s and chemicals are key in this sector.OECDis the organization that develops test methods that are globally accepted and used in thetesting of chemicals. It has been very instrumental in harmonization of ...
OECD GUIDELINE FOR THE TESTING OF CHEMICALS In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method OECD/OCDE 439 Adopted: 22 July 2010 OECD GUIDELINE FOR THE TESTING OF CHEMICALS In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method INTRODUCTION 1. Skin irritation refers to...