OECD Guidance Document 39 Acute Inhalation Toxicity - ICCVAM 热度: BUILDINGPARTNERSHIPSFORPROGRESS Français Home:ChemicalsTesting-Guidelines>Documentation>Documents- Guidelines>OECDTestGuideline401willbedeleted:AMAJORSTEPIN ANIMALWELFARE:OECDREACHESAGREEMENTONTHE ...
[4 ] OECD Guidance Document on Acute Oral Toxicity Testing Series on Testing and Assessent (2001 )24:1-24 [ 5 ] Auletta CS Acute,Subchronic,and Chronic Toxicology,in CRC Handbook of Toxicology (ed by Derelanko MJ and Hollinger MA) ,1995 54 ...
3. Guidance on the selection of the most appropriate test method for a given purpose can be found in the Guidance Document on Acute Oral Toxicity Testing (8). This Guidance Document also contains additional information on the conduct and interpretation of Test Guideline 423. 4. Definitions used...
Organisation for Economic Co-operation and Development, Paris, France.OECD DAC. Applying Strategic Environmental Assessment, Good Practice Guidance For ... OECD 被引量: 401发表: 2006年 The DAC Guidelines - Strategies for Sustainable Development: Guidance for Development Co-operation +:ITJMGO=V^ZUZ...
Guidance on the recognition of evident toxicity has been provided by Sewell et al (2015) [3]: Evident toxicity has been reached if one or more animals display any one of the listed signs (from the day after exposure onwards): tremors, hypoactivity, irregular respiration or bodyweight loss ...
OECD Guidance Document (8). Further groups of animals may be dosed at higher or lower fixed doses, depending on the presence or absence of signs of toxicity or mortality. This procedure continues until the dose causing evident toxicity or no more than one death is identified, or when no ef...
OECD Guidance Document (8). Further groups of animals may be dosed at higher or lower fixed doses, depending on the presence or absence of signs of toxicity or mortality. This procedure continues until the dose causing evident toxicity or no more than one death is identified, or when no ef...
OECD Guidance Document 39 Acute Inhalation Toxicity - ICCVAM 401-ACUTE ORAL TOXICITY (DELETED) OECD Test Guideline 406 Skin Sensitization (1992) - 经济合作发展组织与.ppt 《经济合作发展组织》课件 经济合作与发展组织公司治理原则 国际组织教育改革趋势及热点问题 OECD——经济合...
internationalguidancedocumentonacutetoxicitygivesmoreinformation(12). 3.TheguidelinesignificantlyreducesthenumberofanimalsusedincomparisontoGuideline 401,whichoftenrequiredatleast20animalsinatest:1)thestoppingrulelimitsthenumberof animalsinatest;2)sequentialdosingintroducesfurtherefficienciesinanimaluse;3)initialdosing ...
impendingdeath,arethesubjectofaseparateGuidanceDocument(9). 6.Themethodusespre-defineddosesandtheresultsallowasubstancetoberankedandclassified accordingtotheGloballyHarmonisedSystem for the classification of chemicals which cause acute toxicity (10).