Ocular coherence tomography Anesthetized mice were maintained on a water-based heating pad at 37 °C. Before imaging, lubricant eye drops were instilled on the eyes (Systane Ultra, Alcon), and pupils were dilated using 0.5% tropicamide (Akorn). A lubricant gel (Tears, Alcon) was used to avo...
While a considerable volume of information is accessible on the characterization, formulation, ophthalmic drug delivery, and nanomaterials targeting, data on the toxicity and safety of the above systems and materials are low. Toxicity and safety are critical subjects that are always of concern before ...
As a natural biopolymer with unique viscoelastic property and transparency, HA has been widely used in ophthalmology, particularly in artificial tear solution as a lubricant for dry eyes20. HA-based MN devices have been employed for transdermal delivery of various hydrophilic or hydrophobic therapeutic...
lubricant eye drops, Allergan) at 100 Hz (Fig. 2g). The real-time demonstration of folding and scrubbing the corneal sensor is shown in Supplementary Movie S3. The corresponding results of the impedance as a function of frequency are summarized in Supplementary Figure S10...
Disposable gold-foil corneal contact electrodes (ERG-Jet; Fabrisal SA, La Chaux-de-Fonda, Switzerland) were affixed to the axial corneas with coupling gel (Goniovisc Hypomellose 2.5% Ophthalmic Demulcent Solution USP, HUB Pharmaceuticals LLC, Rancho Cucamongo, CA). Disposable platinum subdermal ...
Hylo-Vision (ii) Artelac Splash MDO, Hyalistil, Optive Fusion, Hylo-Comod and Vismed Multi (iii) Xailin HA (iv) Hylo-Gel Xailin HA is significantly different from all others products with the lowest surface tension recorded.ConclusionsXailin HA is a new hyaluronan-based ocular lubricant. ...
surgery, injury, infection, or inflammation at the front of the eye is typically treated with topical steroid, topical non-steroidal anti-inflammatory drug (NSAID), systemic NSAID, lubricant ointment, gel or drops, bandage contact lens, or a few doses of oral opiate or topical anesthetic. When...
The eye lubricant was uses on an as needed basis. The protocol was varied according the progress of recovery, the sensitivity of the patient to the medications, and other factors as known to one skilled in the art. One drop of drop of cyclosporine (0.05% w/v) composition (liquid solution...
After the rats were anesthetized, the pupil was dilated using a drop of 1% tropicamide ophthalmic solution. A lubricant ocular gel (GenTeal, Alcon Laboratories Inc., Fort Worth, TX, USA) was applied to the whole anterior eye to keep the eye surface hydrated throughout the experiment. The ...
Research Progress of In-Situ Gelling Ophthalmic Drug Delivery System. Asian J. Pharm. Sci. 2019, 14, 1–15. [Google Scholar] [CrossRef] Khan, N.; Aqil, M.; Imam, S.S.; Ali, A. Development and Evaluation of a Novel in Situ Gel of Sparfloxacin for Sustained Ocular Drug Delivery: ...