12.1 Mechanism of Action Octreotide acetate injection exerts pharmacologic actions similar to the natural hormone, somatostatin. It is an even more potent inhibitor of GH, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses luteinizing hormone (LH) response to gonadotropin rele...
Mechanism of Action Somatostatin analog; decreases GH secretion, secretion of gastrin, VIP, glucagon, secretin, serotonin release and pancreatic polypeptide; in acromegaly, octreotide decreases growth hormone and IGF-1 secretion; suppresses LH response to GnRH secretion and decreases splanchnic blood flow...
Octreotide Acetate试剂CAS号:79517-01-4纯度:≥98%化学式:C49H66N10O10S2 2C2H4O2熔点:分子量:1139.36保存温度:+4°C产品介绍:Soluble in methanol.Sandostatin Wang S, Bao Z, Liang QM, et al. Octreotide stimulates somatostatin receptor-induced apoptosis of SW480 colon cancer cells by activation of ...
Octreotide long-acting-release (LAR) is a depot formulation consisting of octreotide acetate encapsulated in microspheres that, administrated intramuscularly (i.m.), gradually releases the octreotide. From:Progress in Brain Research,2010 About this page ...
We hypothesized that octreotide acetate (Sandostatin ), a somatostatin analog, decreases the pancreatic flow rate through a peptide-mediated mechanism and alters pancreatic fluid composition by inhibiting carbonic anhydrase action and circulating peptide levels. To test this hypothesis, we collected ...
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successfully applied to the analysis of commercially available octreotide injection forms. Keywords: hydrophilic interaction liquid chromatography;fluorescence detection;octreotide;octreotide acetate;SMS 201-995;somatostatin 1. Introduction The neuropeptide somatostatin is a cyclic tetradecapeptide originally isolated...