[3] A. C. Walls, et al., Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein.Cell, 2020, 181(2).. [4] D. Wrapp, et al., Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.Science, 2020, 367, ...
Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus.PLoS ONE 12(10): e0186854. Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus.Science 342, 592 (2013);...
[13]Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin. Bioorganic & Medicinal Chemistry Letters,2017 [14]A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemaggl...
Agrimonolide inhibits cancer progression and induces ferroptosis and apoptosis by targeting SCD1 in ovarian cancer cells.Phytomedicine, Volume 101, July 2022, 154102 Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2.International Journal of Biological...
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结构生物学研究是通过解析蛋白质的精细结构,深入理解蛋白质如何在生命活动中进行工作,进而为探寻疾病根源、设计新药提供新路径,迄今为止,已有十余个诺贝尔奖颁给了结构生物学领域的相关科学家。科研界流传了一句话,“想发高分文章,结构少不了”。生命科学领域中结构学相关的分子水平研究已成为一种趋势,这其中需要对蛋白...
Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2.International Journal of Biological Macromolecules, Volume 209, Part A, 1 June 2022, Pages 1379-1388 Structures of Omicron spike complexes and impl...
https://www.cell.com/structure/abstract/S0969-2126(24)00189-8#%20 https://www.nature.com/articles/s41420-024-02005-3 https://www.mdpi.com/1424-8247/17/6/706 https://www.sciencedirect.com/science/article/abs/pii/S0026265X24009585 ...
TheOCTET_STRINGstructure contains a pointer to a string of byte data. Syntax C++ typedefstructtagOCTET_STRING{DWORD dwLength; BYTE *lpValue; } OCTET_STRING, *POCTET_STRING; Members dwLength Type:DWORD The length of the data. lpValue
Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2.International Journal of Biological Macromolecules, Volume 209, Part A, 1 June 2022, Pages 1379-1388 Structures of Omicron spike complexes and implications for neutralizing antibody development.Cell ...