Occupancy Networks: Learning 3D Reconstruction in Function Space Lars Mescheder1 Michael Oechsle1,2 Michael Niemeyer1 Sebastian Nowozin3† Andreas Geiger1 1Autonomous Vision Group, MPI for Intelligent Systems and University of Tu¨bingen 2ETAS GmbH, Stuttgart 3Google AI...
The set of genes repressed (the C4 group) is also common to many cell-types, while the intragenic cluster (C3-group) and the C5 group (unmarked chromatin) are more cell-type specific. Enrichment of TF-binding sites in MYB-peaks—evidence for direct binding The regions occupied by MYB ...
Curve fitting with the one-site model (Equation 2, see Table 2 and Supplementary Table 1, R2 = 0.19–0.71) confirmed that ƒD3 and the individual D3-rich areas have lower ED50 values of buspirone (3.1–5.2 ng/ml, P = 0.003), 5-OH (2.1–2.7 ng/ml, P = 0.003), and 6-OH ...
The structure is tetragonal for all x and the refinement was made assuming the space group P4/mmm. The Mssbauer data reveal three iron sites one of which is assigned to the Cu(2) planes and the other two to the Cu(1) chains. Their occupancy varies with x. The above data are ...
Previous work from our group demonstrated a bimodal switch between ARID1A and ARID1B in the BAF complex during the CNCC specification process3 (Figure S1B). At the onset of neuroectoderm formation, ARID1A protein levels are downregulated and nearly undetectable while ARID1B protein levels increase3...
(LOGR24K) HLQ(IXGLOGR) MODEL(NO) LS_SIZE(100000) STG_DATACLAS(LOGR4K) STG_SIZE(150000) LOWOFFLOAD(0) HIGHOFFLOAD(60) STG_DUPLEX(NO) RETPD(2) AUTODELETE(YES) OFFLOADRECALL(YES) ZAI(NO) ZAIDATA('NO_ZAIDATA') WARNPRIMARY(NO) DASDONLY(NO) DIAG(NO) LOGGERDUPLEX(UNCOND) GROUP(...
immunity and cancer. This would be consistent with recent work showing that NF-κB stimulates the expression of Notch targets HES-5 and Deltex-1 to stimulate marginal zone (MZ) B-cell development [52] and with prior observations from our group that NF-κB can trigger Notch signaling by induc...
Increasing amounts of MNase were used for each sample as indicated by the triangles at the bottom; the lowest level in each group corresponds to no MNase addition, and the highest to 50 units/ml. Marker lanes (M) contain 100-bp DNA ladders. The small arrow in each panel indicates the ...
Previous studies have estimated receptor occupancy by comparing the specific to nonspecific binding ratio in patients to a normal control group mean. The purpose of the present study was to use IBZM SPECT to determine a relationship between dose or serum concentration levels and occupancy for ...