The pathophysiology of OSA is summarized in three steps: firstly, the varied structural and functional determinants of an anatomical predisposition for airway closure, an absolutely essential component for OSA; secondly, the effects of the sleep itself, which emphasizes on mechanisms underlying apnea ...
Related to obstructive apnea:Sleep apnoea,sleep apnea,Obstructive sleep apnea syndrome,Obstructive sleep apnoea ap·ne·a alsoap·noe·a(ăp′nē-ə, ăp-nē′ə) n. Temporary absence or voluntary cessation of breathing. [New Latinapnoea, from Greekapnoia:a-,without; seea-1+pnoiā, -...
pathophysiology of adverse cardiovascular outcomes of obstructive sleep apnea has not been fully elucidated. Matrix metalloproteinases (MMPs) have been associated with both oxidative stress and cardiovascular diseases. Hypoxic conditions were shown to influence MMP expression, secretion and activity. Moreover...
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Definitions Apnea – a temporary absence or cessation of breathing Definitions OSAHS – a condition in which a person experiences repeated episodes of apnoea because of a narrowing or closure of the pharyngeal airway during sleep, resulting in daytime ...
Objective To systematically review the interactions of OSA with cardiovascular pathophysiology and diseases. Data Sources and Study Selection The MEDLINE database from January 1966 to March 2003 was searched using the Medical Subject Headings sleep, sleep apnea, obesity, hypertension, heart failure, cardi...
Kahal H, Kyrou I, Tahrani AA. Obstructive sleep apnoea and polycystic ovary syndrome: A comprehensive review of clinical interactions and underlying pathophysiology. Clin Endocrinol (Oxf). 2017 Oct;87(4):313-319. Gateva A, Kamenov Z, Mondeshki Ts, Bilyukov R, Georgiev O. [Polycystic ovaria...
Continuous beat to beat BP monitoring, though not readily available, also provides more insights into the pathophysiology of the OSA in relation to nocturnal hypertension. More specifically, if it is coupled with sleep studies, OSA related BP surge information can be derived [46]. This in turn,...
Obstructive sleep apnea(OSA) is a condition that negatively affects sleep and health, caused by physical disruption of normal breathing. It may be associated withsnoringand othersymptoms. The upper airway can be obstructed during sleep due to a number of causes, many of them interrelated. The re...
Obesity and obstructive sleep apnea There is a very high prevalence of OSA in individuals and a high prevalence of in patients with OSA. The pathophysiology of OSA is intimately linked to . A... AS Gami,SM Caples,VK Somers - 《Endocrinology & Metabolism Clinics of North America》 被引量:...
This review discusses the pathophysiology and causal relationship between OSA and hypertension, along with the cardiovascular effects of treatment of OSA.doi:10.1586/erc.09.25Das, Aneesa MKhayat, RamiExpert Rev Cardiovasc TherDas AM, Khayat R. Hypertension in obstructive sleep apnea: risk and therapy...