Protein O -glucosylation involves the addition of a 尾 -linked glucose to the hydroxyl group of a serine residue within an epidermal growth factor-like (EGF) repeat. EGF repeats are small protein modules found in
POGLUTs/rumiencoding glucosyltransferases possess a catalytic CAP10 domain and a KDEL-like localization signal. The CAP10 protein was first discovered in aCryptococcus neoformansfungus35and most proteins with CAP10 domain also have an ER-retention signal. BLAST analysis has indicated that POGLUT1 sha...
P46CAP10-like 46 kDa protein; KDELC family like 1; KDELCL1; KTEL (Lys-Tyr-Glu-Leu) containing 1; KTEL motif-containing protein 1; KTELC1; MDS010; MDSRP; MDSRPKTELC1; MGC32995; Myelodysplastic syndromes relative protein; POGLUT1; protein O-glucosyltransferase 1; Rumi; x 010 protein...
POGLUTs/rumiencoding glucosyltransferases possess a catalytic CAP10 domain and a KDEL-like localization signal. The CAP10 protein was first discovered in aCryptococcus neoformansfungus35and most proteins with CAP10 domain also have an ER-retention signal. BLAST analysis has indicated that POGLUT1 sha...
Protein O-glucosylation is a conserved post-translational modification that occurs on epidermal growth factor-like (EGF) repeats harboring the C1-X-S-X-P-C2 consensus sequence. The Drosophila protein O-glucosyltransferase (Poglut) Rumi regulates Notch signaling, but the contribution of protein O-...