We proposed candidate measures, but these require analysis of large glucose datasets, a cumbersome task for individual institutions. We developed an application accessible over the internet that facilitates computation of these performance measures.
OBJECTIVE--Pertussis toxin uncoupling-based studies have shown that Gαi and Gαo can inhibit insulin secretion in pancreatic B-cells. Yet it is unclear whether Gαi and Gαo operate through identical mechanisms and how these G-protein-mediated signals inhibit insulin secretion in vivo. Our ob...
申请(专利权)人: NOVO NORDISK A/S 发明人: TB Kjeldsen,S Ludvigsen 摘要: \"The precursor of insulin or insulin analogue precursor sequence of polinucleotìdeo, expression vector, host cell and.Processes for producing a precursor of insulin or analogue precursor of insulin收藏...
Activation of a novel non-selective cation channel by alloxan and HµOµ in the rat insulin-secreting cell line CRI-G1 来自 Ingenta 喜欢 0 阅读量: 37 作者:P. S. Herson,M. L. J. Ashford 摘要: 8*4 ± 0*9 min to complete and was associated with an increased cellular conductance...
Glucose-responsive formulations of insulin can increase its therapeutic index and reduce the burden of its administration. However, it has been difficult to develop single-dosage formulations that can release insulin in both a sustained and glucose-responsive manner. Here we report the development of ...
求翻译:sistencia a la insulina con o sin intolerancia a la glucosa y un estado proinflamatorio y protrombótico como是什么意思?待解决 悬赏分:1 - 离问题结束还有 sistencia a la insulina con o sin intolerancia a la glucosa y un estado proinflamatorio y protrombótico como...
Más allá del síndrome metabólico. Revista Española de Geriatría y Gerontología 42 , 302-311 Online publication date: 1-Sep-2007. /Zafon C. Envejecimiento y resistencia a la insulina. Mas alla del sindrome metabolico. Rev Esp Geriatr Gerontol. 2007;42:302---11....
We demonstrate that, consistent with augmenting Ampk activity, BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity in high-fat-diet-induced obese mice. Hence, we provide a unique bioactive compound that inhibits pAmpkα disposal. Together, these results ...
申请(专利权)人: LABORATORIOS BETA S.A.发明人:L Ducrey,N Annibali,G Trejo,M Goin 摘要: Method for producing human insulin analogue and a precursor metilotrófica Yeast strain that produces more specifically, the method comprises preparing an inoculum of a Strain of recombinant yeast meti...
PURPOSE: To test the hypothesis that hypertrophic cardiomyopathy during prenatal life in diabetic pregnancies is related to fetal hyperinsulinism. METHODS: Thirty seven fetuses of diabetic mothers and 28 of non-diabetic mothers were studied by echocardiography and fetal insulin levels measured. RESULTS:...