Cellular malondialdehyde (MDA) level was quantified using a lipid peroxidation (MDA) assay kit (Abcam, Cambridge, UK). 2.6. RNA interference, gene transfection, plasmid construction, and RNA-protein pull-down assays Supplementary methods refer to details on target gene silencing, expression induction...
the level of integrin αIIbβ3was negligible at the surface of resting platelets. There was a sharp increase in the level of integrin αIIbβ3following ADP (10μM) treatment, and a significant attenuation in the presence of LGP and the positive control ticagrelor. Similarly, the level of in...
Moreover, a flow cytometry test was performed to measure the level of apoptosis and necrosis. Based on the obtained results, CMC/Fe3O4@SiO2 can be regarded as a novel promising system for cancer therapy. Keywords: carboxymethyl cellulose; quercetin; Fe3O4 nanoparticles; core–shell ...
However, their occurrence in many places simultaneously implies a major paradigmatic shift in the community exposure from a relatively low level to a much higher region where genotoxic outcomes become more common. Secondly, it would be expected that the rising trend in cannabinoid exposure shows a ...
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Among the investigated cells, HCT 116 showed the highest level of DSBs induced by examined pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides (15.8–30.6% of DNA in the tail), while DNA damage levels in BxPC-3 and PC-3 cell lines were in the range of 7.1–10% and 1.5...
Poorly informed pest and disease management strategies can have detrimental effects on the environment, crop quality, crop yield, farmers’ income, and the overall sustainability of agriculture. For this reason, integrated pest and disease management (IP