Self-promoted glycosylation using trichloroacetimidates and sulfonamides have recently been developed. In this communication, we study the parameters controlling the chemoselectivity between a nucleophilic sulfonamide nitrogen and an alcohol, both contained in the same molecule. The influence of solvent ...
GlycosylationSelf‐promotionChemoselectivityStereoselectivityN‐Glycosidesdoi:10.1002/ejoc.202000526Alessandro PinnaDepartment of Chemistry and Industrial Chemistry Università di Genova Genova ItalyChristian Marcus PedersenDepartment of Chemistry University of Copenhagen Universitetsparken 5 2100 Copenhagen Denmark...
O-glycosylation mimics N-glycosylation in the 16-kDa fragment of bovine pro-opiomelanocortin. The major O-glycan attached to Thr-45 carries SO4-4GalNAc bet... (1994) O-glycosylation mimics N-glycosylation in the 16-kDa fragment of bovine pro-opiomelanocortin: The major O-glycan attached to ...
N- and O- glycosylation occur on asparagine and serine/threonine residues, respectively, according to defined sequence motifs in the polypeptide CystatinsDefinitionPrimary Care Trusts (PCTs) of newly synthesized proteins by enzymatic cross-linking of carbohydrate moieties to the polypeptide backbone. N-...
N糖基化位点:N-Glycosylation Site O糖基化位点:O-Glycosylation Site //@Tommy_T:糖基化位点分析:glycosylation site analysis //@Tommy_T:糖基化位点:glycosylation site http://t.cn/A6NmCFkd【转发】@Tom...
N- and O-Glycosylation 喜欢 0 阅读量: 18 作者: M Schwab 摘要: DefinitionDefinitionPrimary Care Trusts (PCTs) of newly synthesized proteins by enzymatic cross-linking of carbohydrate moieties to the polypeptide backbone. N- and O-glycosylation occur on asparagine 年份: 2009 ...
Oglycosylation(o糖基化)讲述.pptx,Introduction to GLYCOBIOLOGY;Chapter 5 O-linked Glycosylation;Mucin-type O-glycans (O-GalNAc) O-glycans in proteoglycan (O-Xyl, O-GalNAc) O-Fuc O-GlcNAc …… Play structural or signal roles;Linkage of Mucin-type O-Glycans
[名词解释] O-linked glycosylation (O-连接的糖基化) 相关知识点: 试题来源: 解析 是将糖链转移到多肽链的丝氨酸、苏氨酸或羟赖氨酸的羟基的氧原子上。O-连接的糖基化是由不同的糖基转移酶催化的,每次加上一个单糖。同复杂的N-连接的糖基化一样,最后一步是加上唾液酸残基,这一反应发生在高尔基体反面膜...
Overproduction of superoxide anion (•O2-) and O-linked β-N-acetylglucosamine (O-GlcNAc)-modification in the vascular system are contributors to endothelial dysfunction. This study tested the hypothesis that increased levels of O-GlcNAc-modified proteins contribute to •O2- production via activatio...
O-glycosylation is the post-translational process whereby carbohydrate is added to hydroxylated amino acids of proteins. The major O-glycosylation pathway in animal cells is involved in the synthesis of oligosaccharides linked by N-acetylgalactosamine to serine or threonine residues in 'mucin-type' prot...