In conclusion, silencing of lncRNA NUTM2A-AS1 inhibited proliferation and induced apoptosis in human glioma cells via the miR-376a-3p/YAP1 axis.doi:10.1186/s13008-024-00122-0Zeng, YuechengYang, ZhenyuYang, YangWang, PengBioMed CentralCell Division...
Conclusion NUTM2A-AS1 knockdown attenuated LPS-induced damage in HDPCs partly through targeting let-7c-5p/HMGB1 axis.doi:10.1016/j.intimp.2021.107497Xuechun WangHuijun SunZhekai HuPeng MeiMin ZhuInternational Immunopharmacology
结果IL-1β诱导的软骨细胞中LncRNA NUTM2A-AS1和TGFα表达升高,miR-183-5p表达降低,软骨细胞活性降低,而凋亡率升高,TNF-α,IL-6水平升高.低表达LncRNA NUTM2A-AS1,低表达TGFα或过表达miR-183-5p后可促进细胞增殖及抑制细胞凋亡,炎症反应.结论低表达LncRNA NUTM2A-AS1通过调控miR-183-5p/TGFα抑制IL-1β...
pcDNA si-LncRNA NUTM2A-ASI model group; realtime fluorescent quantitative PCR (RT-qPCR ) was used to detect the expression levels of LncRNA NUTM2A-AS1, miR-183-Sp and TGFa mRNA; cell counting kit 8 ( CCK-8 ) was used to detect cell viabili...
结果IL-1β诱导的软骨细胞中LncRNA NUTM2A-AS1和TGFα表达升高,miR-183-5p表达降低,软骨细胞活性降低,而凋亡率升高,TNF-α,IL-6水平升高.低表达LncRNA NUTM2A-AS1,低表达TGFα或过表达miR-183-5p后可促进细胞增殖及抑制细胞凋亡,炎症反应.结论低表达LncRNA NUTM2A-AS1通过调控miR-183-5p/TGFα抑制IL-1β...
The role of lncRNA NUTM2A-AS1 has been explored in various cancers, but its function in drug-resistant NB progression is unclear. Our study found that NUTM2A-AS1 expression in cisplatin-resistant NB cells increased in a time- and dose-dependent manner. Knockdown of NUTM2A-AS1 significantly ...
Long Non-Coding RNA NUTM2A-AS1/miR-376a-3p/PRMT5 Axis Promotes Prostate Cancer Progressiondoi:10.56434/j.arch.esp.urol.20247702.23Hongfen HanZheng LiLei BiJing ZhangArchivos Espaoles de Urología
Methods: A Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to detect lncRNA NUTM2A-AS1 expression in CRC cell lines. Cell counting kit 8 (CCK-8) assay and flow cytometry were used to examine the biological functions of lncRNA NUTM2A-AS1 in the proliferation and ...