We performed two GWAS using maxdrinks as an excessive alcohol consumption phenotype: one in 118 extended families (N = 2,322) selected from the Collaborative Study on the Genetics of Alcoholism (COGA), and the other in a case–control sample (N = 2,593) derived from the Study of ...
A total of 21 013 CNVs were predicted to overlap at least one of 5848 different RefSeq genes across the study cohort. The average number of CNVs overlapping genes per individual was 9.1 (range 1–107). Deletions overlapping genes were detected approxi- mately three times as often than ...
Approaches for predicting CNV pathogenicity can be divided into three types. In the first approach, aggregation of per-base single nucleotide polymorphism (SNP) pathogenicity scores within CNV intervals are used to determine the pathogenic effect of CNVs. One of the examples is SVscore [22], whi...
This has to be one of the best Chinese sit-down restaurants in the City. It just feels like a warm spot to come out of the cold and relax Read more Written January 6, 2022 This review is the subjective opinion of a Tripadvisor member and not of Tripadvisor LLC. Tripadvisor perf...