Alarm as the Number of Prostate Cancer Cases Skyrockets
However, among females, breast cancer is by far the most common form of new cancer cases. In fact, breast cancer is the most prevalent cancer worldwide, followed by prostate cancer. Prostate cancer is a very close second to lung cancer among the cancers with the highest rates of new cases...
abaccalaureate 学士学位 [translate] aSpecial Char.Class 正在翻译,请等待... [translate] athe relatively small number of early onset prostate cancer cases, leading to limited power to detect associations between 2D : 4D and prostate cancer risk for younger men. 正在翻译,请等待... [translate] ...
a large number of unnecessary biopsies are performed each year, and the quality of life of a very large number of men is adversely affected.(3,4) The American Cancer Society estimates that approximately 233,000 new cases of prostate cancer will be diagnosed...
A nonparametric Bayes classifier was trained using the PI-RADS score, prostate-specific antigen (PSA) density, lesion size, zone, and location as covariates. Results The most relevant histopathologic diagnosis of the index lesion was detected by the first biopsy core in 331 cases (73%), by ...
Mitotic activity was assessed as before11 with a mean mitotic index of 12 per 2 mm2 (range 0–56). For all cases, hormone receptor and HER2 status were reassessed as described previously.9 Tissue microarray (TMA) slides were used for immunohistochemical staining of ER, PR, and chromogenic ...
tumors characterized as part of the Cancer Genome Atlas (TCGA). We validated some 7790 somatic coding mutations, achieving 93% sensitivity and 85% precision for single nucleotide variant (SNV) detection. Exome-based CNA analysis identified 29 large-scale alterations and 619 focal events per tumor...
An accurate diagnosis of ERBB2 amplification is critical, because trastuzumab is solely designed (and effective) only for tumors with ERBB2 amplification. Not only the mechanism of action, but also fatal cardiac side effects [42, 43] and high costs (more than $100,000/year per patient) [44...
The methylation data generated using the Illumina 27K platform support the existence of only one or a few methylation sites per gene. Collinearity among sites were low, and thus they were modeled simultaneously in a gene-level regression model (as discussed herein) without concern. In cases ...
at least two cases of ovarian cancer in the same family line; (b) at least one case of ovarian cancer and at least one case of breast cancer in the same family line; (c) at least one woman with both breast and ovarian cancer; (d) at least one woman with bilateral ovarian cancer....