Number of top predicted genes that overlap between different models.Ohad, Manor
ESTIMATING GENE NUMBERS 399 TABLE 1 Values of probability of detection (Pa, ) for a pair of linked loci as a function of generation (n) and recombination fraction (c), and corresponding ratio d of predicted number of effective factors to number of genes C n c 05 02 0-1 005 0-01 0...
The turnover numberkcat, a measure of enzyme efficiency, is central to understanding cellular physiology and resource allocation. As experimentalkcatestimates are unavailable for the vast majority of enzymatic reactions, the development of accurate computational prediction methods is highly desirable. However...
California Researchers Call Into Question The Estimated Number of Human Genes. Reports on the findings of scientists at Scripps Research Institute in La Jolla, California, and Genomics Institute of Novartis Research Institute on the e... Hensley,Scott - 《Wall Street Journal Eastern Edition》 被引...
Predicted expression patterns across hundreds of genes were experimentally validated. Prediction success was critically dependent on how a multi-copy gene interacted with other genes in the network model. This strategy provides a template for the inference, prediction, and testing of genetically complex ...
Vernalization sensitivity in Arabidopsis thaliana (Brassicaceae): the effects of latitude and FLC variation Latitudinal variation in climate is predicted to select for latitudinal differentiation in sensitivity to the environmental cues that signal plants to flow... JR Stinchcombe,AL Caicedo,R Hopkins,.....
Methods: The relationship between the copy number of the genes encoding the fourth component of complement (C4A and C4B) and LTA 252 single-nucleotide polymorphism (SNP) on the one hand and mortality after acute myocardial infarction (AMI) was studied in 142 Icelandic patients. The number of ...
Subsequently, the pathogenic CNV-related phenotypes (HPO terms) from the DECIPHER database v10.1 were mapped onto the second layer of the HP-HS to extract rare disease-related phenotypes. The cancer predisposition genes (CPGs) used were collected from a previous study [61], which curated 58 ...
D. Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein. Mol. Cell. Biol. 26, 5406–5420 (2006). CAS PubMed Central PubMed Google Scholar Lin, F. L., Sperle, K. & Sternberg, N. Model for homologous ...
towards a value of low density (Fig.1a). We found that this nonlinear trend follows a power law (d ∼ n−γ) withγ = 0.78 ≈ 1 (R2 = 0.96), strongly suggesting that a hyperbolic (inverse) behavior governs the relationship between density and number of genes. ...