Ultrastructure of mitochondria-containing nuclei in human myocardial cells The ultrastructure of myocardial cell nuclei was examined in a group of 12 patients undergoing cardiopulmonary bypass surgery. In one patient (aged 60 year... H Jensen,ETS Saetersdal - Virchows Archiv B Cell Pathology Zell-pa...
Mitochondria as a therapeutic target in heart failure. J Am Coll Cardiol 2013; 61: 599–610. Article CAS Google Scholar Purdue MP, Hofmann JN, Colt JS, Hoxha M, Ruterbusch JJ, Davis FG et al. A case-control study of peripheral blood mitochondrial DNA copy number and risk of renal ...
After some time in space, mitochondria, the energy powerhouses of cells, often didn’t work as well as they should.Those findings are consistent with samples from NASA’s Twin Study. Before retiring, astronaut Scott Kelly spent nearly a year aboard the International Space Station. His twin, ...
The ETC in mitochondria, particularly complex I and III, also serves as a prime mechanism for the generation of free radicals.15,16 The number of mitochondria per cell is related to the energy demands of the cell, and the copy number of mitochondrial DNA (mtDNA) can vary depending upon ...
根据文章最后一段“Damage to mitochondria may be a common factor in spaceflight health risks, the team now concludes.”(研究小组得出结论,线粒体损伤可能是太空飞行健康风险的一个常见因素。)及“If mitochondria are the cause, dealing with problems of them could help protect future astronauts. Some ...
Mitochondria are the location of the citric acid or Krebs Cycle, which produces the majority of ATP for cellular work. Each cell has multiple mitochondria and each mitochondrion contains one or more copies of its own circular genome (mtDNA), which is 16569 bases in length and encodes 37 genes...
“The idea is not only to look at one type of chemical,”Beheshti says. Rather, they wanted to “look at the living system as a whole”. And in doing that, they found a common theme. After some time in space, mitochondria, the energy powerhouses of cells, often didn’t work as ...
Years later, armed with pen and paper, I was able to show that glutamine consumption increases because the mitochondria have a limited capacity to turn over the NADH generated during aerobic biosynthesis from glucose [38]. I make an emphasis on the use of pen and paper in an attempt to ...
Eukaryotic mitochondria contain a circular genome of ~16 kb encoding two rRNAs, 22 tRNAs, 13 genes for electron transport chain subunits and at least two hormone-like peptides1,2. Changes in mitochondrial DNA (mtDNA) copy number (mCN) and deletion frequency are linked to the natural aging...
Changes in nerve cell cytoplasm with its correlated axon and dendritic processes, together with changes in the size, shape, position and general character of its various constituents—the Nissl bodies, canalicular apparatus, mitochondria... Francesca,Nicholson - 《Journal of Nervous & Mental Disease》...