Glial cells express CD81, and antibodies directed against this protein suppress the mitotic activity of cultured cells. In this study, we examine the effects of the CD81 -/- mutation on the CNS of mature mice. These mice have extremely large brains, as much as 30% larger than the brains...
The total cell number in the entricular/subventricular zone, VZ/SZ (germinal matrix), was reduced by a factor of five from week 22 until term. A histological differentiation between neurons and glial cells was not possible. The optical fractionator was used to estimate the total cell population...
We have studied the reaction of glial cells in mice treated with an intraperitoneal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), ... M Kohutnicka,E Lewandowska,I Kurkowska-Jastrzebska,... - 《Immunopharmacology》 被引量: 631发表: 1998年 Mass Spectrometric Quantific...
Gtx: a novel murine homeobox-containing gene, expressed specifically in glial cells of the brain and germ cells of testis, has a transcriptional repressor activity in vitro for a serum-inducible promoter. EMBO J 1993;12:1387–1401. 40. Duclos A, Charbonnier F, Chambon P, et al. ...
Reported values in the literature on the number of cells in the body differ by orders of magnitude and are very seldom supported by any measurements or calculations. Here, we integrate the most up-to-date information on the number of human and bacterial cells in the body. We estimate the ...
Glial Hedgehog and lipid metabolism regulate neural stem cell proliferation in Drosophila The final size and function of the adult central nervous system (CNS) is determined by neuronal lineages generated by neural stem cells (NSCs) in the developing brain. In Drosophila, NSCs called neuroblasts (...
Although astrocytes constitute nearly half of the cells in our brain, their function is a long-standing neurobiological mystery. Here we show by quantal analyses, FM1-43 imaging, immunostaining, and electron microscopy that few synapses form in the absence of glial cells and that the few synapses...
The changing number of cells in the human fetal forebrain and its subdivisions: a stereological analysis. Cereb Cortex. 2003;13(2):115-12212507942PubMedGoogle ScholarCrossref 24. West MJ. New stereological methods for counting neurons. Neurobiol Aging. 1993;14(4):275-2858367009PubMedGoogle ...
used to detect the expression of neural stem cell specific marker nestin and the expression of serum-induced neuron tubulin 2 and glial fibrillary acidic protein.RESULTS ①The neural stem cells amount of rat with 12.5 days of gestational age was the largest and that of 13.5 days was the ...
GFAP glial fibrillary acidic protein Keywords Epilepsy Seizure frequency Hippocampus Neuronal cell Non-neuronal cell 1. Introduction Temporal lobe epilepsy (TLE) is a neurological disorder that involves disruption of the brain’s normal activity due to neuronal hyperexcitability in temporal lobe regions (...