We show that when gene activity is autoregulated by a positive feedback, the change in number of gene alleles may have dramatic consequences for its regulation and may not be compensated by the change of efficiency of mRNA synthesis per allele....
We show that when gene activity is autoregulated by a positive feedback, the change in number of gene alleles may have dramatic consequences for its regulation and may not be compensated by the change of efficiency of mRNA synthesis per allele. 展开 ...
In populations of facultatively sexual organisms, the proportion of sexually produced offspring contributed to each generation is a critical determinant of their evolutionary potential. However, estimating this parameter in natural populations has proved
On the number of self-incompatibility alleles maintained in equilibrium by a given mutation rate in a population of a given size: a re-examination. Biometrics 16, 61–85 (1960). Google Scholar Wright, S. The distribution of self-incompatibility alleles in populations. Evolution 18, 609–619...
Considering a random mating population of finite size, the variance of the number of loci having a given gene frequency was derived under the assumption of a steady flux of mutations. The variance of average heterozygosity among populations was also derived under the same assumption. It was shown...
We found the captive population to be genetically more variable than the largest natural population in Europe, both in terms of mean number of alleles per locus and mean observed and expected heterozygosity. Allelic diversity of the captive population was higher than, and mean heterozygosity ...
Imprinted genes are characterized by differential allelic expression, which is dependent on the parental origin of the alleles and is closely regulated in normal tissues [1,2,3,4,5,6,7]. Many imprinted genes promote body growth, cell metabolism, and cell proliferation in normal embryonic or pos...
SNPQC: This is a measure of how well genotype alleles are resolved in the microarray data. In other words, it estimates the distributions of homozygous AA, heterozygous AB, and homozygous BB alleles and calculates ...
The number of animals with alternative alleles for the CNVRs ranged from five (CNVR13, CNVR46) to 270 (CNVR15). The predicted status for the CNVRs was 19 (38.7%) for gain, eight (16.3%) for loss and 22 (45%) for regions with gain or loss status in different animals (Table 1)...
In thetRNA-Phegene family, the expression of at least sixtRNA-Phealleles is required for embryonic viability andtRNA-Phe-1-1is most important for development and survival. Our results reveal that the multi-copy configuration of tRNA genes is required to buffer translation and viability in ...