Keywords: beauvericin; apoptosis; oxidative stress; Nrf2; autophagy Key Contribution: The study firstly confirmed that BEA induced oxidative stress; accompanied by overproduction of ROS, Nrf2 activation and translocation to the nucleus, and initiated autophagy, which provides a novel insight into the mol...
Nrf2 Translocation from cytoplasm to nucleus.Yuichi MasudaNosratola D. VaziriShiri LiAimee LeMohammad HajighasemiOssarehLourdes RoblesClarence E. FosterMichael J. StamosIsmail AlAbodullahCamillo Ricordi
Degradation of Nrf2 in the cytoplasm, mediated by Keap1-Cullin3/RING box1 (Cul3-Rbx1) E3 ubiquitin ligase and the proteasome, is considered the primary pathway controlling the cellular abundance of Nrf2. Although the nucleus has been implicated in the degradation of Nrf2, little information is ...
PTE could promote the nuclear translocation of Nrf2 in NPCs. In addition, Nrf2 silence reversed the inhibitory effect of PTE on the production of NO and PGE2 and the expression of COX-2 and iNOS. These results indicate that PTE inhibits inflammation in the rat nucleus pulposus by promoting ...
He Xiaoqing,Lin Gary X,Chen Michael G,Zhang Jennifer X,Ma Qiang.Protection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association.Toxicological sciences : an official journal of the Society of ...
Ma, "Pro- tection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and dis- rupting the nuclear Nrf2/Keap1 association," Toxicological Sciences, vol. 98, no. 1, pp. 298-309, 2007....
3 - 74 Inhibition of Nrf2 Transposition to Nucleus Induced Radiosensitization of Liver Cancer 英语阅读理解物理研究摘要:Wang ZhenhuaSun ChaoZhang Hong中国科学院近代物理研究所和兰州重离子研究装置年报:英文版
Nrf2INTERVERTEBRAL DISC DEGENERATIONEXPRESSIONTISSUEAims This study was performed to explore the effect of melatonin on pyroptosis in nucleus pulpo-sus cells (NPCs) and the underlying mechanism of that effect.Methods This experiment included three patients diagnosed with lumbar disc herniation who failed ...
Effect of SFN on translocation of Nrf2 into cell nucleus.Yongping, BaoWei, WangZhiGang, ZhouChanghao, Sun
Aldosterone-induced Phosphorylation of Nrf2 and its Subsequent Translocation into the Nucleus does not lead to Upregulation of Nrf2 Target Genes in Tubuli of Mouse Kidneys - ScienceDirectdoi:10.1016/j.freeradbiomed.2020.10.058Ronja BalhornNicole Schupp...