伏隔核(Nucleus Accumbens,NAc)是大脑奖赏系统的核心结构,位于基底核与边缘系统交界处,通过多巴胺能通路调控动机、奖赏感知及行为决策。其功能异常与成瘾、抑郁症等精神疾病密切相关,临床研究通过干预其神经元活动探索治疗新方法。以下从结构、功能、疾病关联及临床应用四方面展开。 一、位置...
在草原田鼠“为爱奔跑”的同时,研究者们使用一根毫秒级微型光纤传感器来追踪动物大脑中伏隔核的活动。伏隔核(nucleus accumbens,NAcc)是位于大脑两侧波纹体中的一组神经元,与奖赏、快乐、成瘾等脑部活动密切相关。人类神经影像研究表明,当我们握住伴侣的手时,伏隔核的活动会大量增加。每当传感器检测到多巴胺浓度...
ShellThenucleus accumbens shell(NAcc shell) is a substructure of the nucleus accumbens. The shell and core together form the entire nucleus accumbens.Location:The shell is the outer region of the nucleus accumbens, and – unlike the core – is considered to be part of the extended amygdala, ...
The nucleus accumbens (NAcc) is a brain region involved in functions ranging from motivation and reward to feeding and drug addiction. The NAcc is typically divided into two major subdivisions, the shell and the core. The primary output neurons of both of these areas are medium spiny neurons ...
The nucleus accumbens (NAc) plays an important role in various emotional and motivational behaviors that rely on heightened wakefulness. However, the neura
The nucleus accumbens (NAc) is a key component of the neural processes regulating impulsivity. ? The extent and pattern of involvement of the NAc, and its subregions, the core and the shell, vary among different facets of impulsivity. ? There is strong evidence supporting the involvement of ...
Accumbens nucleus;NAc;NAcc;Nucleus accumbens septi Definition Nucleus accumbens (NAc) is a brain area found in basal forebrain. It is present in between caudate and putamen nuclei of basal ganglia. NAc is also the main component of ventral striatum. Most importantly NAc is implicated in reward...
The nucleus accumbens core (NAcc core) is the inner substructure of the nucleus accumbens. Location: The nucleus accumbens core is part of the ventral striatum, located within the basal ganglia. Cell types: The core of the NAcc is made up mainly of medium spiny neurons containing mainly D1...
Nucleus accumbens Thenucleus accumbens(NAcc) has been implicated as aneuromodulationtarget since the earlier days of this technology (Bishop et al., 1963). It is known to play key roles in thecognitive processingof motivation, reward (i.e.,incentive salience, pleasure, and positive reinforcement...
所有病例均在局麻下行双侧扣带回及双侧伏核(Nucleus accumbens NAc)毁损。手术前后采用视觉模拟评分(Visual analog s… www.cmt.com.cn|基于3个网页 2. 伏隔核 ...用古柯硷建立的小鼠制约场地偏好(CPP)时,表现在伏隔核(nucleus accumbens NAc)的相关记忆候选蛋白质群。