The novel feature of the structure is the manner in which the two chains are held together by the purine and pyrimidine bases... The (bases) are joined together in pairs, a single base from one chain being hydrogen-bonded to a single base from the other chain, so that the two lie ...
The same linear group of polynucleotide chains may pack together parallel or paracrystalline material.In all cases the x-ray diffraction photograph consists of two regions, one determined largely by the regular spacing of nucleotides along the chain, and the other by the longer spacings of the ...
In some embodiments, nucleotide synthesis comprises the formation of a nucleoside (the nitrogenous base joined to a sugar). The sugar involved in the synthesis and structure of a nucleotide may be either ribose or deoxyribose; in the latter case, the prefix ‘deoxy’ may be added before the ...
the genetic information in DNA can be ‘transcribed’ into mRNA, and proteins can be translated from the information in mRNA, in a process called translation, in which protein subunits (amino acids) are brought close enough to bond, in order (as dictated...
joined to the bead are still available for subsequent incorporation events. This also results in a reduction of the apparent binding affinity between the nucleotide-bead conjugates to the enzyme, allowing lower background signal, and thus higher signal-to-noise ratios. In a further embodiment, the...