The gene in is responsible for the isozyme conversion of . We analyzed the 1,664-nucleotide sequence of a chromosomal DNA segment that contained the gene and its flanking regions. The predicted product contained 345 amino acids with an estimated molecular weight of 37,919. The 24-amino-acid ...
The iap gene in Escherichia coli is responsible for the isozyme conversion of alkaline phosphatase. We analyzed the 1,664-nucleotide sequence of a chromosomal DNA segment that contained the iap gene and its flanking regions. The predicted iap product contained 345 amino acids with an estimated mole...
In general, the IAP nucleic acids of the invention have 95% or higher identity to SEQ ID NO:1 and the IAP of the invention have 90% or higher identity to SEQ ID NO:3.Bruce D. HammockQihong HuangSusumu MaedaUSUS6570069 * Feb 10, 2000 May 27, 2003 Regents Of The University Of ...
Base bias also appears incodon usagesin a manner dependent on the organism. Among the combinations of eight least-used codons, the bias for adinucleotidesequence CG (including CGA and CGG for Arg) has been found to be most remarkable and is shared byE. coli, yeast, fruit fly, and primates...
as an effort toward development of new inhibitors. Results and Discussions Preparation of Park's nucleotide analogues and evaluation of their substrate activity. As shown in Fig. 3, O-debenzylation of 1 followed by a phosphorylation and phosphitylation/oxidation sequence gave the phosphate 2...
NOD-like receptor CARD domain 3, NLRC3, is another member of NLRs that has been recently investigated. NLRC3 possesses the conserved structure of NLR including an LRR repeat, NACHT domain, and N-terminal effectordomain of unknown function. Based on itsgeneticsequence, the NLR...
Exposure to oxPAPC alters the endothelial transcriptome5 and the complex changes are a con- sequence of various regulatory circuits acting in concert. If ana- lyzed at a single time point, the endothelial responses to oxPAPC are overwhelmingly complex. To address this, we went beyond ...
Missense and nonsense mutations reported in the literature from patients with inflammatory disease were chosen for study that span the protein-coding sequence of XIAP and inserted with an N-terminal myc tag downstream of an antibiotic resistance gene in the lentiviral construct (Fig. 5a). To ...
(ref.34). The sequences surrounding Ser118, Ser125 and Ser304 are well conserved in vertebrate PDE4 orthologues (Supplementary Fig. 3A) and in the different mouse PDE4 isoforms (Supplementary Fig. 3B). When Ala residues were introduced by site-directed mutagenesis to replace each Ser, the ...
The invention relates to an isolated polynucleotide having a polynucleotide sequence which codes for the cobW gene, and a host-vector system having a coryneform host bact