There are three major obstacles to the analysis of the nucleotide sequence in a DNA molecule starting from a known location in the DNA molecule. First, it is difficult to obtain large quantities of homogeneous DNA. Second, even the smallest DNA molecules contain several thousand nucleotides which ...
Two procedures have been developed and applied to the determination of the 3′ terminal sequences of λ DNA and φ80 DNA. In the first procedure, each 3′ terminus was specifically labeled with a single 32P-nucleotide. Radioactive oligonucleotides of different lengths were obtained by partial pan...
[Nature of the nucleotide sequence of DNA in fishes] Mazin AL, Vaniushin BF, Belozerski AN. AL Mazin,BF Vaniushin,AN Belozerskiĭ - 《Doklady Akademii Nauk Sssr》 被引量: 0发表: 1973年 Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene Comparison...
A DNA sequence for the genome of bacteriophage φX174 of approximately 5,375 nucleotides has been determined using the rapid and simple ‘plus and minus’ method. The sequence identifies many of the features responsible for the production of the proteins
We have determined the nucleotide sequence of ten 240 bp repeated sequences of the DNA intergenic spacer present in circular DNA molecules purified from D melanogaster embryos. No significant difference was found with the sequence of the chromosomal units. This suggests that most of the circular mol...
The nucleotide sequence of a 1.76 Kbp segment from rat liver mitochondrial DNA has been determined. It contains the gene for the cytochrome b apoprotein and the tRNA genes for threonine, glutamic acid, and proline. The arrangement of these genes in rat liver mitochondria is the same as in hu...
Restriction analysis and cloning of virus-specific double-stranded DNA isolated from plants infected with wheat dwarf virus (WDV) indicated that the virus genome, like that of maize streak virus (MSV), consists of a single DNA circle. The complete nucleotide sequence of cloned WDV DNA (2749 ...
Related to nucleotide sequences:DNA sequences nu·cle·o·tide (no͞o′klē-ə-tīd′, nyo͞o′-) n. Any of a group of compounds consisting of a nucleoside combined with a phosphate group and constituting the units that make up DNA and RNA molecules. ...
DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype. Two HLA class II beta-chain clones from a cell line homozygous for the DR1 haplotype have been characterized and sequenced. They represent a DR beta chain ... J,I,Bell,.....
Only two groups of plant viruses, the caulimoviruses1,2 and the geminiviruses3, are known to contain a genome of DNA. Unlike that of the caulimoviruses, the genome of the geminivinises is composed of single-stranded, covalently-closed circles of DNA. The