its nucleoside and 5'-nucleotide. Biochem. Pharmacol., 25. 2413-2415, 1976.Streeter DG, Koyama HH. Inhibition of purine nucleotide biosynthesis by 3-deazaguanine, its nucleoside and 5 -nucleotide. Biochem Pharm
1-alkoxymethyl-5-alkyl-6-naphthylmethyl uracils, which are novel 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) analogues, were synthesized for evaluation as selective and potent nonnucleoside human immunodeficiency virus (HIV)-1 reverse transcriptase inhibitors. The anti-HIV-1 activity...
The chapter summarizes the progress that has been made in the area of "sugar nucleotide" metabolism. The chapter discusses the enzymic synthesis of glycosyl esters of nucleoside 5'-pyrophosphates. Some sugar nucleotides are produced by "cross reactions" of biosynthetic enzymes that have broad ...